33 citations,
September 2014 in “Reproductive Biology and Endocrinology” High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.
26 citations,
August 2014 in “Genetic Testing and Molecular Biomarkers” High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.
17 citations,
December 2008 in “Dermatology” Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.
1 citations,
November 2017 in “International journal of clinical endocrinology and metabolism” The supplement with Myo-inositol and D-chiro-inositol improves metabolic symptoms in PCOS, especially when combined with metformin.
4 citations,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” A certain genetic variation is linked to a higher risk of polycystic ovarian syndrome.
200 citations,
October 2009 in “European journal of endocrinology” Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
7 citations,
October 2020 in “Journal of Clinical Medicine” Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.
August 2024 in “Archives of Women s Mental Health” Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.
7 citations,
August 2019 in “Journal of Ovarian Research” Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.
2 citations,
September 2009 in “Nurse Prescribing” PCOS affects many women, causing various symptoms and health risks, and is managed through lifestyle changes, medication, and support groups.
30 citations,
September 2016 in “Aging Cell” Low selenium levels can extend lifespan but worsen health issues.
8 citations,
September 2018 in “Journal of Cosmetic Dermatology” Lower irisin levels in the blood may indicate more severe acne.
149 citations,
December 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.
34 citations,
July 2014 in “Indian Dermatology Online Journal” Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.
3 citations,
May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
34 citations,
January 2008 in “International Review of Neurobiology” Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
21 citations,
September 2017 in “Journal of Obstetrics and Gynaecology Research” Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.
August 2013 in “Fertility and sterility” Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.
10 citations,
September 2015 in “Gynecological Endocrinology” Both treatments reduced excessive hair growth in PCOS, but there was no difference in weight, hair score, hormone levels, or insulin resistance.
1 citations,
January 2001 in “Drug and therapeutics bulletin” The document concludes that management strategies for PCOS are important due to its common occurrence and associated health risks.
December 2022 in “Cumhuriyet medical journal” Different PCOS subgroups have similar metabolic features, but those without menstrual problems have milder issues.
17 citations,
January 2020 in “The World Journal of Men's Health” Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
21 citations,
August 2014 in “Gynecological Endocrinology” Higher hs-CRP levels in Indian adolescent women with PCOS are more related to BMI than PCOS itself.
August 2013 in “Fertility and Sterility” Hair loss is common in women with PCOS and is linked to symptoms like acne and excess hair but not to worse metabolic health.
11 citations,
September 2012 in “Journal of obstetrics and gynaecology Canada” Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
13 citations,
June 2018 in “Journal of Womens Health” Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.
14 citations,
January 2008 in “Gynecological Endocrinology” High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.
15 citations,
October 2011 in “Gynecological Endocrinology” Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.
270 citations,
April 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.
16 citations,
March 2011 in “Pediatric diabetes” Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.