112 citations
,
January 2013 in “Experimental dermatology” This article offers a viewpoint on hidradenitis suppurativa pathogenesis, suggesting that impaired Notch signalling from γ-secretase mutations may drive inflammation and link the condition to other Th17-driven diseases.
77 citations
,
April 2004 in “Gene expression patterns” This study observed specific expression patterns of three zebrafish estrogen receptor genes during development, highlighting robust co-expression of esr2a and esr2b in primary neuromasts, branchial arches, and other tissues.
56 citations
,
March 2016 in “International Wound Journal” This review concludes that autologous split-thickness skin grafting remains the gold standard for safety and efficacy in treating chronic leg ulcers, with greater success in venous ulcers.
52 citations
,
May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that overexpression of parathyroid hormone-related protein in mice resulted in 30–40% shorter hair due to premature transition into the catagen phase of the hair cycle.
45 citations
,
July 2022 in “Frontiers in Pharmacology” This review discusses the mechanisms and targets of natural products for treating nonhealing wounds and reports no new experimental results, highlighting potential pathways and cytokines involved.
42 citations
,
March 2018 in “PLOS Biology” This study found that autophagy plays a novel role in human hair growth, with altered autophagic flux during hair development phases influencing hair follicle behavior in a preclinical model.
41 citations
,
January 2020 in “Journal of Ovarian Research” This review suggests that quercetin supplementation may benefit ovarian functions and hormonal levels in polycystic ovary syndrome, though further high-quality trials are needed for confirmation.
32 citations
,
March 2020 in “Drug Design Development and Therapy” This review examines the pharmacology, clinical efficacy, and adverse effects of oral finasteride for female pattern hair loss, and discusses potential new treatments like topical finasteride and dutasteride, but reports no new clinical results.
26 citations
,
June 2011 in “Molecular Medicine” This study found that high doses of progesterone significantly inhibited neuroblastoma growth in both in vitro and mouse models, while showing selective toxicity and minimal harm to healthy cells.
24 citations
,
March 2024 in “Antioxidants” In this review, researchers reported that cinnamon and ginger supplementation may benefit PCOS patients by improving hormonal status, lipid profiles, obesity, and insulin resistance through oxidative stress and inflammation reduction.
24 citations
,
November 2019 in “Dermatologic Surgery” This review evaluates the use of platelet-rich plasma in dermatology, highlighting favorable outcomes in several areas, especially androgenetic alopecia, despite a lack of large randomized controlled trials and consistency in protocols.
23 citations
,
October 2018 in “Australasian Journal of Dermatology” This review highlights that frontal fibrosing alopecia’s increasing incidence may involve immune, genetic, hormonal, and environmental factors, yet its pathogenesis remains complex and not fully understood.
22 citations
,
January 2006 in “Journal of Structural Biology” Hair follicles form hard α-keratin filaments in four steps, showing structural differences.
19 citations
,
May 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the progress in research on topical formulations for treating alopecia, highlighting potential advantages of advanced formulation technologies but reporting no new clinical results.
16 citations
,
August 2018 in “Journal of empirical legal studies” This study found that the elimination of the tampon tax in New Jersey was fully passed on to consumers, benefiting low-income consumers more than high-income consumers.
16 citations
,
March 2025 in “International Journal of Molecular Sciences” This review analyzed 12 clinical studies on extracellular vesicle therapies, finding potential benefits for skin aging, acne scars, alopecia, and wound healing, but highlighted significant challenges like production standardization and lack of large-scale studies.
16 citations
,
January 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that serum PSA levels are higher in hirsute women and can be significantly reduced by antiandrogen treatment, suggesting PSA as a marker of androgen action in females.
8 citations
,
September 2020 in “British Journal of Dermatology” This study explored whether bald characters are disproportionately portrayed as villains in Hollywood films but reports no new empirical results; the authors suggest this pattern may reflect a societal bias associating alopecia with immorality.
7 citations
,
August 2024 in “Skin Research and Technology” The study's findings are unreliable due to retraction.
7 citations
,
February 2004 in “Clinical and Experimental Ophthalmology” This case report details a 65-year-old woman who developed malignant melanoma in her right eye socket following previous eye trauma, treated by orbital exenteration.
5 citations
,
April 2024 in “BMJ Open” This scoping review revealed that methods for measuring traumatic scar thickness using ultrasound are inconsistently reported and mainly remain in early research phases, highlighting a need for standardizing these methods to bridge the gap to routine clinical practice.
5 citations
,
September 2023 in “Clinical Endocrinology” This study suggests revising PCOS diagnostic criteria to integrate the polymenorrhoea subcategory due to shared metabolic dysfunctions with oligomenorrhoea.
3 citations
,
November 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review evaluated existing studies on platelet-rich plasma for facial rejuvenation and found limited clinical evidence supporting its effectiveness, suggesting that more research is needed to establish its utility.
3 citations
,
September 2020 in “Bladder cancer” In this study, 5α-reductase inhibitors were found to have no significant impact on preventing tumorigenesis or progression in in vitro models of urothelial cancer.
2 citations
,
September 2025 in “Food Science and Biotechnology” This study found that Placenderm®, a porcine placenta peptide, may promote hair follicle regeneration and enhance hair growth in mice by balancing growth-promoting and inhibitory factors.
2 citations
,
March 2023 in “Shiraz E-Medical Journal” This study reported that 87.8% of formerly hospitalized COVID-19 patients experienced at least one symptom of long COVID, with hair loss and depression being the most common.
2 citations
,
January 2020 in “International Journal of Cosmetic Science” In this in vitro study, niacinamide was found not to stimulate VEGF synthesis across a wide range of doses.
2 citations
,
June 2011 in “Journal of the American Academy of Dermatology” Melanoma occurs more on the left side of the body, unlike other skin cancers.
1 citations
,
June 2026 in “Dermato” This narrative review found that ritlecitinib shows consistent effectiveness and a favorable safety profile for treating alopecia areata in clinical trials and real-world settings, with progressive hair regrowth observed, particularly when treatment is initiated early and maintained appropriately.
1 citations
,
October 2025 in “Journal of Clinical Medicine” In this systematic review, researchers reported that various types of laser therapy effectively treat hidradenitis suppurativa at different severity stages, with each laser offering specific benefits such as lesion removal, inflammation reduction, and improved quality of life.