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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.

SSRIs can cause hair loss, especially sertraline, with higher risk in women.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Laser hair removal is safe and effective for fair-skinned people with dark hair, and using eflornithine with laser treatments can improve results.

Primary care for PCOS focuses on lifestyle changes, medication based on symptoms, and mental health, with diabetes screening and specialist referral for severe cases.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Early diagnosis and treatment of PCOS in young people is important to prevent long-term health problems.

Taking a small dose of prednisone before menstruation can almost completely prevent premenstrual acne with few side effects.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

New method effectively detects illegal hormones in anti-aging foods.

A man got a rare rash from the drug topiramate, which went away after he stopped taking it.

Women with PCOS may have a higher risk of respiratory and ear infections due to slower nasal mucociliary clearance.

Individualized treatment plans, including lifestyle changes and specific medications, are crucial for managing PCOS in adolescents.

Estrogens and progesterone are key in regulating melasma pigmentation.

Forensic hair analysis for drugs is now more reliable and accurate.

The document lists various dermatology topics, treatments, and diagnostic methods.

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

High doses of certain vitamins can cause serious side effects and health risks.

Effective management of hyperandrogenism in young women requires accurate diagnosis and tailored treatment.

Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.

Spironolactone improved symptoms in women with hormonal imbalances and had few side effects.

A woman's male-pattern facial hair growth was caused by a rare malignant ovarian tumor that was difficult to diagnose and treat.

Metformin lowers gremlin-1 and improves insulin resistance in women with PCOS.

Uterine transplants for transgender women are feasible but need more research.