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Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

Estradiol-rich plasma can increase hair density faster and more effectively in male pattern baldness treatment than regular plasma.

Sebocytes play a key role in controlling androgen levels in human skin.

Androgens can help prevent memory problems caused by apoE4.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Finasteride helps reduce heart issues and improves heart function.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.

Finasteride reduces movement issues in Parkinson's disease rats.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Finasteride causes harmful organ changes in female mice.