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Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

The effects of estrogen on human scalp hair growth are unclear and need more research.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

Older women often have vulva issues due to less estrogen, which can be misdiagnosed and lead to wrong treatments.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.

Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.