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This study found that DGAT1 exhibits additional acyltransferase activities in vitro, including MGAT, wax synthase, and ARAT activities, suggesting these could be relevant to its in vivo functions.

This study found that DGAT1 functions as a key enzyme in murine skin to regulate retinoic acid levels and prevent retinoid toxicity, impacting hair cycle and sensitivity to retinol.

This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.

This study found that several dehydroepiandrosterone ester derivatives effectively reduced prostate and seminal vesicle weight in gonadectomized hamsters treated with testosterone, demonstrating potential antiandrogen effects comparable to Finasteride.

This study reported that newly synthesized progesterone derivatives significantly reduced prostate weight in testosterone-treated hamsters, with 5alpha-reductase inhibitory activity dependent on the size of the substituent at C-17.

This study found that four new progesterone derivatives reduced prostate weight in gonadectomized hamsters, suggesting potent in vivo antiandrogenic effects similar to finasteride.

This study found that aliphatic ester moieties in 16-formyl-17-methoxy dehydroepiandrosterone derivatives increased their potency as 5α-reductase type 2 inhibitors in vitro compared to finasteride.

This study found that methyl nonanoate and methyl caprate significantly enhanced the skin penetration of minoxidil compared to solutions with other common enhancers like Azone, DMSO, or DEET.

This study found that in hamster flank organs, 17βC inhibited enlargement caused by topical testosterone but not by DHT, suggesting potential use in androgen-related skin disorders like acne.

This study identified a new compound from fermented Carica papaya L. with moderate antioxidant and potent hair growth-stimulating activities in vitro.

This study found that women with PCOS have higher follicular fluid levels of testosterone and IL-6, despite similar NEFA levels to non-PCOS women, suggesting increased lipotoxicity impact on androgenesis in PCOS.

This review highlights the potential benefits of spironolactone in dermatology, particularly for female acne, supporting its safety over long-term use without extensive testing, but presents no new clinical results.

This study found that ketorolac tert-butyl ester enhances skin permeation and follicular absorption compared to ketorolac, highlighting the role of lipophilicity and solubility in prodrug design.

Fumaric acid esters might help treat alopecia areata, but more research is needed.

This thesis explores the synthesis and antiproliferative properties of phenylpropanoid sucrose esters, noting the absence of synthetic methods for most of this compound class due to their structural complexity.

This research examined krill oil's effects on benign prostatic hyperplasia and found that it inhibited the growth of prostate cells in vitro and reduced prostate size and weight in a BPH rat model, suggesting potential as a prophylactic or therapeutic agent for BPH.

This meeting review discusses recent advances in systemic psoriasis treatments, emphasizing the impact of dimethylfumarate monotherapy on understanding psoriasis and treatment strategies; it reports no new clinical results.

This report describes a rare case of epidermolysis bullosa acquisita in a child developing during therapy with squaric acid dibutyl ester for alopecia areata, suggesting a possible link between the medication and disease onset.

This research indicates that KCED-1 and KCED-2 effectively induce adiponectin production in human subcutaneous fat, which may promote hair growth on the scalp.

In this study, the authors observed that Staphylococcus aureus lipase gehB is crucial for bacterial penetration of hair follicles in mice, implicating lipases in inflammation and skin damage.

This study found that some synthesized 17-oximino-5-androsten-3β-yl esters demonstrated stronger cytotoxicity and antiandrogenic activity against prostate cancer cells than finasteride.

Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.

This study concluded that spikenard specimens in Renaissance Italian herbaria are attributed to Nardostachys jatamansi, a plant used in traditional medicine and cosmetics.

This study found that pregnane derivatives with higher lipophilicity, like compound 9d, had stronger androgen receptor binding and greater antiandrogenic effects in rats, correlating relative binding affinity with log P values.

This study found that chronic administration of finasteride in rats led to significant alterations in the epididymis and compromised sperm quality, effects that persisted even after 30 days of treatment cessation.

This study found that laser ablation-inductively coupled plasma-mass spectrometry can effectively reconstruct time-resolved mercury exposure in micrometer segments of a single hair strand from fish-eaters.

This study found that applying a combination of pyridine‐2, 4‐dicarboxylic acid diethyl ester and resveratrol significantly increased hair density in Caucasian women after 1.5 months, potentially due to their synergistic effect on the HIF‐1α pathway.

This study found that dexamethasone treatment inhibited the inflammatory response and the induction of ornithine decarboxylase activity in mouse skin after TPA application, although the effect on ODC was weaker during the hyperplastic stage.

This study found that overexpression of PKCα in mouse epidermis increases expression of specific proinflammatory mediators and induces inflammation but does not significantly affect epidermal differentiation, proliferation, or tumor promotion with TPA.