2 citations
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January 2023 in “Sexual Medicine” This study found that the MTCK, a masturbation aid, significantly improved intravaginal ejaculation latency time and some related sexual function scores in men with premature ejaculation after 8 weeks of use.
74 citations
,
July 1991 in “The Journal of Urology” This study found that topically applied minoxidil was more effective than nitroglycerin and placebo in enhancing penile diameter, rigidity, and arterial flow, with the most pronounced effects in patients with neurogenic impotence.
15 citations
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June 1995 in “The Journal of Clinical Endocrinology and Metabolism” This study found that finasteride significantly reduced dihydrotestosterone levels but did not provide clear evidence of impaired libido or erectile function compared to placebo in men.
14 citations
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June 1995 in “The Journal of Clinical Endocrinology and Metabolism” October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This piece describes the EndoPump Male Enhancement supplement, which claims to enhance erections and libido, but notes that there is insufficient medical evidence supporting the efficacy of its ingredients for sexual health.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews the benefits of Truman Plus Male Enhancement for testosterone levels and sexual health, but it does not present any new clinical study results.
2 citations
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October 2020 in “Más dermatología” Choose between topical and oral minoxidil for hair growth based on personal tolerance and side effects.
March 2023 in “Revista Chilena de Urología” This review discusses post-finasteride syndrome, highlighting occasional adverse sexual and systemic effects in men and women, but reports no new research findings while emphasizing the need for better education about the drug's risks.
44 citations
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July 2011 in “Dermatologic Therapy” This study found that finasteride 1 mg was effective in improving androgenetic alopecia over 10 years in men, particularly those older than 30, with some reporting beneficial results even after 5 years.
5 citations
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January 2024 in “Reproductive Medicine and Biology” In this review, extensive analysis using conditional mutant mice revealed that androgen and Wnt signals play crucial roles in the development and function of male external genitalia and erectile tissue, while also exploring various regulatory factors involved in their pathogenesis.
July 2023 in “World Journal of Biology Pharmacy and Health Sciences” This research suggests that the drugs trazodone and chlorpromazine, which have effects on specific receptors, may help restore libido synaptic circuits and potentially treat sexual dysfunction associated with post-SSRI and post-finasteride syndromes.
February 2013 in “Journal of The American Academy of Dermatology” Using hair loss drugs finasteride and dutasteride may cause sexual side effects.
28 citations
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November 2017 in “Molecular and cellular endocrinology” This review examines the roles of testosterone, dihydrotestosterone, and estradiol in activating male sexual behavior in laboratory animals and humans, reporting no new clinical results.
June 2018 in “The Journal of Sexual Medicine” This study used high-resolution ultrasound to investigate the pathophysiology of persistent erectile dysfunction in young men who used the drug finasteride, observing differences in erectile tissue homogeneity compared to control subjects without finasteride exposure.
September 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Scientists successfully created fully functional hair follicles using bioengineering methods and stem cells.
13 citations
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November 2012 in “PubMed” This study found that in men with sexual dysfunction, use of 5ARI may reduce sexual drive and spontaneous erections without worsening pre-existing erectile or ejaculatory issues.
January 2020 in “Fertility and Sterility” This review discusses rare and controversial conditions like painful nocturnal erections and post-finasteride syndrome, calling attention to these issues but providing no new clinical findings.
January 2017 in “Clinical pharmacist” Long use of finasteride and dutasteride can cause long-term erection problems.
March 2026 in “Canadian Urological Association Journal” This study observed that complementary and alternative medicine, often marketed to men as ways to enhance "optimization," "recovery," and "vitality," has become mainstream, with many believing in its benefits for testosterone, erections, libido, hair loss, and sperm quality.
February 2025 in “International Urology and Nephrology” In this study, mild improvements in erectile function, penile sensitivity, and nocturnal erections were observed in male patients with post-drug syndrome following a 16-week treatment targeting the peripheral nerves of the genitalia, but significant symptoms persisted, indicating further research is essential.
November 2023 in “Magna Scientia Advanced Research and Reviews” The researchers proposed that an epigenetic change in brain androgen receptors caused by finasteride could lead to post finasteride syndrome, while trazodone might reverse this effect by altering the epigenetic expression related to erection and libido.
6 citations
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September 2010 in “Current Urology Reports” This review focuses on recent advancements in understanding and treating ischemic and nonischemic priapism, but does not present new clinical results.
28 citations
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May 1994 in “The Journal of Urology” This study found that topical application of 2% minoxidil solution was not effective in improving erectile dysfunction in the majority of participants.
21 citations
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July 2018 in “The Journal of Sexual Medicine” This article updates the process of care model for evaluating erectile dysfunction, emphasizing comprehensive evaluation and a combination of pharmacotherapy and counseling tailored to patient dynamics.
14 citations
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August 1997 in “The Journal of Urology” Finasteride can cause enlarged breasts.
January 2018 in “Urologe A” In this case report, botulinum neurotoxin injections were associated with a 6-month cessation of priapism episodes in a young man with recurring low-flow priapism, following unsuccessful conventional treatments.
January 2003 in “Zhonghua shiyan waike zazhi” This study found that androgen is essential for erectile function in rats, and suggests that its effects may be partly mediated through nitric oxide synthase positive neurons in the medial preoptic area.
25 citations
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February 2012 in “The Journal of Sexual Medicine” In this study, oral finasteride treatment for four weeks reduced the weight of the corpus cavernosum in rats but did not significantly affect erectile function.
12 citations
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October 2012 in “International Braz J Urol” This study suggests that a low daily dose of finasteride may be effective in reducing recurrent priapism episodes in children and adolescents with sickle cell disease, though larger controlled studies are needed to confirm these findings.
3 citations
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January 2015 in “Social Science Research Network” This study discusses the role of physicians and pharmaceutical companies as entrepreneurial actors in off-label drug use, arguing they may advance patient care more quickly than regulatory agencies.