research 0873 Modeling junctional epidermolysis bullosa using tissue-engineered skin substitutes
Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.
Search
for
Sort by
Research
300-330 / 1000+ resultsresearch A linear and reticulate crusted keratotic papulopustular eruption: a rare presentation of PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) complex
A rare skin reaction from cancer treatment was successfully managed with topical treatments and antihistamines.
research 877 Loss of UBE2N in keratinocytes leads to skin inflammation and immune infiltration through IRAK1/4-mediated processes
This study found that deleting Ube2n in adult mouse skin leads to inflammation and other skin changes, and identifies IRAK1/4 as potential treatment targets for inflammatory skin disorders.
research Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization
This study found that in squamous cell carcinomas, the inhibition of the tumor-suppressor function of TAp73β by ΔNp63α occurs through promoter squelching, not direct protein interaction.
research Cosmetic Potency of Puerariae Radix in Dermal Fibroblasts
In this study, the ethanol extract of Puerariae Radix was found to promote proliferation and ERK activation in human dermal fibroblasts, suggesting its potential as a new cosmetic ingredient.
research Administration of dutasteride in animal models of retinitis pigmentosa
In this study, dutasteride treatment in retinitis pigmentosa mice increased photoreceptor survival and reduced glial activation, suggesting it may offer a neuroprotective effect.
research A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders
This study developed an in vitro model using NTERT keratinocytes expressing AEC-related TP63 mutations, which replicated skin defects observed in AEC patients and offers a valuable tool for understanding the disorder and developing new treatments.
research Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models
This study found that Guilu Erxian Glue significantly alleviates various doxorubicin-induced side effects in mice, enhancing exercise capacity and reducing oxidative stress and inflammation.
research The abnormal, mis-localizated HR bmh protein associates with members of the protein processing machinery in the cytoplasm
This study found that the mutant hairless rhino bald protein in mice interacts with the vitamin D receptor but cannot repress its transactivation and shows abnormal cellular localization.
research PRX102 Participates in Root Hairs Tip Growth of Rice
This study found that PRX102, a peroxidase with a unique polar localization pattern, plays a role in root hair growth by aiding the transport of materials to the tips of growing root hairs.
research MP44-04 TRENDS IN 5-ALPHA REDUCTASE INHIBITOR USE BEFORE AND AFTER THE FOOD AND DRUG ADMINISTRATION SAFETY WARNING
After the FDA's 2011 warning about a potential prostate cancer risk with 5-alpha reductase inhibitors, this study observed a significant decrease in their prescriptions, notably a 49% drop among men with benign prostatic hyperplasia, while primary care providers reduced prescriptions by 60%.
research Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity
A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
research The Comparative Safety of Epirubicin and Cyclophosphamide versus Docetaxel and Cyclophosphamide in Lymph Node-Negative, HR-Positive, HER2-Negative Breast Cancer (ELEGANT): A Randomized Trial
In this study, EC chemotherapy was found to be noninferior to TC in causing grade 3 or 4 neutropenia among HR+/HER2-negative breast cancer patients, but EC was associated with more other adverse events.
research DHT and E2 synthesis-related proteins and receptors expression in male yak skin during different hair follicle stages
This study found that in male yaks, 5α-red1 may play a crucial role in synthesizing DHT to promote hair follicle growth, while E2 synthesized by epithelial cells may inhibit this growth through ERα.
research [Purification of recombinant fusion polypeptide hEGF-AWRK6 and effect on wound healing and infection of burn model mice].
In a mouse model of infected burns, this study found that treatment with recombinant fusion peptide EK significantly decreased Pseudomonas aeruginosa colony count and improved wound healing rates compared to controls.
research Erlotinib-related Severe Hair Loss with Severe Exanthematous Drug Eruption: A Case Report
This case report details a 54-year-old woman with metastatic non-small-cell lung cancer who experienced severe hair loss and exanthematous drug eruption, potentially linked to erlotinib hypersensitivity.
research Genetic variants in AR and SHBG and resistance to hormonal castration in prostate cancer
In this study, researchers reported that the SHBG +5790 G>A polymorphism was associated with an increased risk of developing resistance to hormonal castration in advanced prostate cancer patients.
research Fibroblast growth factor 21 is differentially expressed in flank skin and regulates the proliferation of hair follicles in yak
research 69-Year-Old Man With Dysuria and Right Lower Abdominal Pain
This case report describes a 69-year-old man diagnosed with stage 3 acute kidney injury secondary to new IgG kappa light chain multiple myeloma, where treatment with bortezomib-based therapy showed potential for kidney function salvage.
research 96 Hair Restoration
The document cannot be summarized as it is not provided or is unclear.
research TOXICOLOGICAL STUDY ON THE HEALTH EFFECTS OF LONG TERM EXPOSURE TO BENZENE IN BENZENE FILLING WORKERS, QASSIM REGION, KSA
In this study, long-term occupational exposure to benzene in fueling workers was associated with increased skin diseases, altered blood cell counts, and elevated liver enzyme levels compared to overseers.
research A Novel Role of IL-17+ Cell Subsets in Ross River Virus-Induced Arthritic Disease
This study found that in a mouse model of Ross River virus-induced joint inflammation, targeting IL-17A and IL-17A/F heterodimers reduced disease severity.
research UJI AKTIVITAS FORMULASI SEDIAAN SHAMPO EKSTRAK ETANOL 96% DAUN PARE (Momordica Charantia L.) TERHADAP PERTUMBUHAN RAMBUT PADA KELINCI
This study concluded that bitter melon leaf ethanol extract can be effectively formulated into a shampoo that meets quality standards and promotes rabbit hair growth.
research CD34 and BerEP4 Are Helpful to Distinguish Basaloid Tricholemmoma From Basal Cell Carcinoma
This study found that immunohistochemistry can effectively distinguish between tricholemmoma and basal cell carcinoma, with BerEP4 and CD34 serving as key differentiators.
research A novel missense mutation in the mouse hairless gene causes irreversible hair loss: Genetic and molecular analyses of Hrm1Enu
A new genetic mutation in mice causes permanent hair loss and skin wrinkling.
research 265 Modulation of disease-central cytokine pathways with TAK-279, a highly selective oral tyrosine kinase 2 (TYK2) inhibitor, defines clinical response in patients with psoriasis
TAK-279 effectively reduces psoriasis symptoms and is safe.
research Strontium Ranelate Promotes Chondrogenesis Through Inhibition of the Wnt/β-catenin Pathway
This study found that strontium ranelate may promote cartilage regeneration by enhancing chondrogenic differentiation and inhibiting the Wnt/β-catenin signaling pathway in rat models of cartilage defects.
research 5 alpha-reductase-2 gene mutations in the Dominican Republic.
This study identified multiple mutations in the 5 alpha-reductase-2 gene among male pseudohermaphrodites in the Dominican Republic, suggesting they do not share a common ancestry.
research 128 Bimekizumab led to rapid & deep normalisation of molecular signatures associated with PASI sub-components, preceding clinical skin clearance
Bimekizumab quickly improves psoriasis symptoms and skin at the molecular level.
research A kindred with mutant IKAROS and autoimmunity
This study found that a novel IKZF1 mutation, p.L188V, is linked to juvenile-onset systemic lupus erythematosus and alters B-cell activation by disrupting normal DNA binding.