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Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.

Dermoscopy has improved skin cancer diagnosis and has expanding applications in dermatology, but requires staying updated with new research and techniques.

Microneedles help treat hair loss by improving hair surroundings and promoting growth.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

The 3D electrospun fibrous sponge is promising for tissue repair and healing diabetic wounds.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Improved dermabrasion techniques in 1987 led to better treatment results for skin issues like acne scars.

Cell aging can be both good and bad for tissue repair.

Minoxidil helps treat eyebrow thinning, monilethrix, early hair loss, and shortens chemo-related hair loss.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Olive leaf compound oleuropein helps grow hair in mice.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

Early onset hair loss linked to genetics and androgen levels.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.