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    Glossary Epithelial Sac

    small, enclosed structure of epithelial cells around hair follicle

    An epithelial sac is a small, enclosed structure composed of epithelial cells, which are cells that line the surfaces and cavities of the body. In the context of hair biology, an epithelial sac can refer to the structure that surrounds the developing hair follicle, playing a crucial role in the formation and growth of hair. This sac provides a protective environment and supplies necessary nutrients to the growing hair shaft.

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    1. Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration Journal of Investigative Dermatology · 2001 · 72 citations
    2. Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle 1998 · 32 citations
    3. Exogen involves gradual release of the hair club fibre in the vibrissa follicle model Experimental Dermatology · 2009 · 14 citations
    4. Outer root sheath keratinization in anagen and catagen of the mammalian hair follicle. A seventh distinct type of keratinization in the hair follicle: trichilemmal keratinization. PubMed · 1981 · 59 citations
    5. Mesenchymal stem cell-derived exosomes ameliorate gentamicin-induced vestibular hair cell injury by regulating the SNARE pathway and enhancing autophagy Stem Cell Research & Therapy · 2025 · 1 citations
    6. Evaluation of immunoreactivity of normal tissues from dogs, using monoclonal antibody B72.3 American Journal of Veterinary Research · 1994
    7. Histological Study for Skin of Horse 2023
    8. The Dermis of Millivora Capenesis American International Journal of Humanities Arts and Social Sciences · 2019
    9. Cornified Epithelial Teeth of Jawless Vertebrates Contain Proteins Similar to Keratin-Associated Proteins of Mammalian Skin Appendages Journal of Developmental Biology · 2025
    10. Transglutaminase Activity Is Conserved in Stratified Epithelia and Skin Appendages of Mammals and Birds International journal of molecular sciences · 2023 · 8 citations
    11. Skin Appendage Proteins of Tetrapods: Building Blocks of Claws, Feathers, Hair and Other Cornified Epithelial Structures Animals · 2025
    12. Quiescent Tissue Stem Cells Evade Immune Surveillance Immunity · 2018 · 169 citations
    13. Double mutation of <i>claudin‐1</i> and <i>claudin‐3</i> causes alopecia in infant mice Annals of the New York Academy of Sciences · 2023 · 3 citations
    14. Hoxc13 and homologs of mammalian hair keratins are required for the cornification of nuptial pads in Xenopus frogs Communications Biology · 2026
    15. Convergent evolution has led to the loss of claw proteins in snakes and worm lizards Genome Biology and Evolution · 2024
    16. Choreographing Immunity in the Skin Epithelial Barrier Immunity · 2019 · 57 citations
    17. Isolation of epithelial stem cells from dermis by a three-dimensional culture system Journal of Cellular Biochemistry · 2006 · 38 citations
    18. Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    19. Epithelial Skin Biology Current Topics in Developmental Biology · 2016 · 118 citations
    20. EFFECT OF "AMINOPTERIN" ON EPITHELIAL TISSUES Archives of Dermatology · 1951 · 114 citations
    21. Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity Stem cells · 2018 · 24 citations
    22. Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration Journal of Visualized Experiments · 2013 · 6 citations
    23. Lineage potential, plasticity and environmental reprogramming of epithelial stem/progenitor cells Biochemical Society Transactions · 2014 · 4 citations
    24. 1458 EMT-inhibiting transcription factor Ovol2 regulates directional cell migration and proliferation in adult skin epithelia Journal of Investigative Dermatology · 2018
    25. Isolation and Characterization of Cutaneous Epithelial Stem Cells Humana Press eBooks · 2013 · 4 citations
    26. Salicylate induces epithelial actin reorganization via activation of the AMP-activated protein kinase and promotes wound healing and contraction in mice Scientific Reports · 2024 · 8 citations
    27. Evidence for murine cutaneous immune surveillance localized to hair follicle epithelium Frontiers in Cell and Developmental Biology · 2026
    28. Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen American Journal of Pathology · 2003 · 91 citations
    29. Follicular dermal papilla structures by organization of epithelial and mesenchymal cells in interfacial polyelectrolyte complex fibers Biomaterials · 2013 · 40 citations
    30. Data from Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity 2023