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Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Imiquimod can cause rare skin side effects, some irreversible, and long-term follow-up is important for users.

Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.

Alopecia areata causes unpredictable hair loss and emotional distress, with no cure and limited treatment options.

Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

Early intervention and tailored management can reduce skin side effects from cancer treatments.

The cornified cell envelope forms a protective barrier in skin and hair, using specific proteins and lipids to maintain effectiveness.

A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.

Women with newly diagnosed PCOS may have worse gum health than those treated for PCOS.

A compromised gut may trigger the autoimmune hair loss condition Alopecia Areata.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

The skin and thymus develop similarly to protect and support immunity.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Hair in mammals likely evolved from glandular structures, not scales.

Intense pulsed light treatment mainly damages pigmented hair parts but spares stem cells, allowing hair to regrow.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

Research on the human skin microbiome has grown, focusing on skin health and diseases, with more studies needed on antibiotic resistance and AI applications.

The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.

Mice healed without scars as fetuses but developed scars as adults, suggesting scarless healing might be replicated with further research.

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.