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This review discusses the classic skin characteristics of hypothyroidism, notably generalized myxedema caused by increased glycosaminoglycan deposition, and reports no clinical results.

In this study, hyperplastic layers of scabietic sheep skin showed expansive keratin labeling, indicating altered keratin expression compared to healthy skin.

This study identified a single autosomal recessive gene responsible for hypotrichosis in a mutant rabbit strain, affecting hair growth and causing epidermal and hair follicle abnormalities.

This study presents the first reported case of a collision tumor consisting of basal cell carcinoma and cutaneous leiomyosarcoma, emphasizing the need for pathologists to recognize such combinations.

This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.

This review discusses the common dermatologic side effects of epidermal growth factor receptor inhibitors and provides practical guidance for recognizing and managing these effects; it reports no new clinical results.

This study found that melatonin treatment increased epidermal thickness, subcutaneous fat, and dermal-related factors in postmenopausal rats, suggesting benefits for skin structure after menopause.

This study found that intradermal bleomycin injections induced dermal fibrosis in C57BL/6 mice, evidenced by hair follicle obliteration and dermal thickening, though no significant trends in gene expression were observed, indicating the need for further research to understand the link between fibrosis and dyschromia.

This study found that skin fibroblasts in mice arise from two distinct lineages which contribute differently to dermal structure and repair, impacting hair follicle formation during wound healing.

This narrative review examines the interactions between skin stem cells and their niches, finding new insights from advancements in genetic and imaging tools but reporting no new experimental results.

This study found that the administration of the mutant BRAF inhibitor dabrafenib in patients with metastatic melanoma was associated with various skin lesions, including keratinocytic proliferation that sometimes showed low-grade malignancy features.

This study suggests that intermediate-size hyaluronate fragments may enhance keratinocyte proliferation and improve skin thickness in atrophic conditions through a CD44-dependent mechanism.

This review summarizes adverse events associated with EGFR-targeting cancer therapies, such as skin rashes and lung disease, and reports no new clinical results.

In a transgenic mouse model, this study found that overexpression of keratin 16 in skin keratinocytes led to hyperkeratosis and increased EGF receptor signaling, altering skin cell behavior and structure.

In this study, researchers found that depleting mtDNA in mice caused skin wrinkles and hair loss but restoring mitochondrial function reversed these effects, highlighting mtDNA's significant role in skin and hair health.

In this study, researchers found that disrupting the PRL gene in mice led to earlier hair molting, especially in females, suggesting that PRL inhibits murine hair cycle events.

This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.

This study found that Notch-related genes, including Notch1 and Notch2, and their ligands and regulators, have distinct patterns of expression during mouse hair vibrissa follicle development and the adult hair cycle.

This article reviews common hair growth abnormalities in children, emphasizing the importance of distinguishing normal development from potential signs of metabolic disorders and indicates no new clinical results.

This study found that inactivating CerS4 in mice led to hair follicle stem cell exhaustion and hair loss, indicating its role in regulating hair regeneration through ceramide composition and signaling pathways.

This study found that K15 is variably expressed in sheep and mouse hair follicles, with specific patterns suggesting a role in the early stages of keratinocyte differentiation.

This study found that combining platelet-rich plasma with adipose-derived mesenchymal stem cells significantly improved diabetic wound healing in rats by enhancing angiogenesis and modulating the Notch signaling pathway.

This review summarizes recent discoveries about how tissue-resident stem cells interact with their environments during normal conditions and after injury, without reporting new results.

Overexpressing the epigen gene in mice leads to enlarged sebaceous glands and greasy fur.

This review discusses the role of defensin peptides in stem cell activation for potential skin rejuvenation therapies and reports no new clinical findings, emphasizing the need for further studies.

This study found that impaired TCF/Lef1 signaling in mice leads to significant skin barrier defects due to altered lipid metabolism and epidermal differentiation.

Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.

This study identified the placenta at the base of the ovary as the origin of poplar seed hair development and detailed transcriptome dynamics during the growth process.

This study found that women with androgenetic alopecia showing a positive immunoreactant profile responded well to combined therapy with minocycline, topical steroids, and red light, indicating an immunologically driven trigger.

This monograph reviews the significant progress in skin biochemistry research over eight to ten years, highlighting key areas and identifying gaps in interpretation.