research The Role of Glucosylceramides in Keratinocyte Differentiation and Epidermal Barrier Function
Glucosylceramides are essential for healthy skin and proper wound healing.
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research Dandruff Lesional Scalp Skin Exhibits Epidermal T Cell Infiltration and a Weakened Hair Follicle Immune Privilege
Dandruff is linked to increased T cells and weakened immune protection in hair follicles.
research Pain Digital Biomarker Detection by Epidermal Biopotential Flexible Sensor and AI-Based System
A new pain-measuring system using sensors and AI can effectively detect pain in mice, which may help assess pain in humans and develop treatments.
research Regulation of Epidermal Proliferation and Hair Follicle Cycling by Synthetic Photostable Retinoid EC23
The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.
research DNA Dioxygenases TET Regulate Keratin Gene Expression and Enhancer Networks Within Lineage-Specific Gene Loci During Epidermal and Hair Follicle-Specific Keratinocyte Differentiation
TET enzymes are important for skin and hair development by controlling gene activity in specific areas.
research Cutaneous Responses to Systemic Iron: A Potential Role for Epidermal Turnover in Mammalian Iron Excretion
Skin may help in getting rid of excess iron through the process of skin cell renewal.
research Decision Letter: Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research Chromatin Architectural Protein CTCF Controls Epidermal Barrier Formation, Hair Follicle Fate Maintenance, and Suppresses Inflammatory Responses in the Skin Epithelium
The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
research The Dark and the Bright Sides of the Transcription Factor Nrf2 in Skin Protection and Disease
Nrf2 helps protect skin from damage but too much can cause skin problems.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
research Toxic Epidermal Necrolysis Caused by Skin Hypersensitivity to Monosulfiram
A woman's severe skin reaction was caused by an allergy to a skin treatment.
research Loss of Epidermal Evi/Wls Results in a Phenotype Resembling Psoriasiform Dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research Keratinocyte-Derived Follistatin Regulates Epidermal Homeostasis and Wound Repair
Activin activation in skin cells speeds up wound healing without affecting scar quality.
research Epigenetic Control of Adult Stem Cell Function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Lipid Analysis of Follicular Casts from Cyanoacrylate Strips as a New Method for Studying Therapeutic Effects of Anti-Acne Agents
The method effectively measures lipid changes and drug effects on skin follicles.
research Graft-Versus-Host Reaction: Cutaneous Manifestations Following Bone Marrow Transplantation
Skin changes help detect graft-versus-host reaction early after bone marrow transplants.
research Epigenetic Control of Skin and Hair Regeneration After Wounding
Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
research Building and Maintaining the Skin
Three types of stem cells help maintain and repair skin, responding to health and environmental changes.
research Histochemical Evidence of Mucosubstances in the Metaplastic Epidermis and Hair Follicles Produced In Vitro in the Presence of Excess Vitamin A
Excess vitamin A changes skin and hair follicle development and affects polysaccharide distribution.
research Basal Keratinocytes Exhibit Age-Related Epigenetic and Transcriptomic Alterations Resulting in an Altered Metabolic Profile
Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.
research Treatment of Acne with Intermittent Isotretinoin: Cohort Study
Intermittent isotretinoin can cause various skin, hair, and nail changes.
research Keratin and Skin Disorders
Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
research Topoisomerase-Interacting Agents
Topoisomerase inhibitors can cause hair loss, skin rash, hand-foot syndrome, and nail changes.
research Changes in the Hair Growth Cycle in Women with Non-Scarring Alopecia
Certain growth factors affect hair loss in women and could be targeted for treatment.
research Follicular Mycosis Fungoides Associated With Lithium
Lithium can cause skin changes similar to mycosis fungoides.
research Madarosis, Milphosis, Eyelash Trichomegaly, and Dermatochalasis: Conditions Affecting the Periocular Area
The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.
research Identification of Differentially Expressed Genes in Actinic Keratosis Samples Treated with Ingenol Mebutate Gel
Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.
research Nuclear Topology, Epigenetics, and Keratinocyte Differentiation
Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.
research Cryo-EM and Molecular Dynamics of TRPV3 Channel in Activated State Reveal Structural Features Implicated in Severe Itch and Hyperkeratosis
The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.
research Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.