9 citations
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August 2021 in “Biomedicines” This study found that 17β-estradiol was the most powerful hormone for inducing APE1/Ref-1 secretion in cultured vascular endothelial cells, with secretion occurring through exosomes dependent on estrogen receptors and intracellular calcium.
29 citations
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September 2017 in “Oncology and therapy” This review discusses the common dermatologic side effects of epidermal growth factor receptor inhibitors and provides practical guidance for recognizing and managing these effects; it reports no new clinical results.
This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.
January 2025 in “Journal of Prescribing Practice” March 2026 in “The Aging Male” This retrospective pharmacovigilance study reviewed adverse event reports from 2004 to 2025 for drugs treating benign prostatic hyperplasia, identifying distinct safety signals for α1-blockers, 5ARIs, and PDE5I, including some potential new adverse events that require further investigation.
16 citations
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May 2004 in “Hair transplant forum international” This article describes efforts in the field of hair restoration to achieve complete results in fewer sessions, but it does not report new clinical outcomes.
222 citations
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October 2014 in “Annual Review of Pharmacology and Toxicology” This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.
61 citations
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April 2023 in “Advanced Materials” This study introduced a viscoelastic dry electrode that successfully reduces motion artifacts in EP monitoring on hairy skin, maintaining stable performance for up to 48 days.
January 2024 in “Skin appendage disorders” In this case report, a 31-year-old diabetic and obese male was diagnosed with follicular psoriasis, a rare variant characterized by scaly follicular papules, using dermoscopy and histopathology; treatment with topical mometasone furoate and oral levocetirizine led to complete lesion resolution within a month.
1 citations
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January 2014 In this study, the release rate of Finasteride from Eudragit matrix tablets was found to be significantly influenced by the drug/Eudragit ratio and polymer viscosity, with formulation F9 being the most effective.
20 citations
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October 2001 in “British Journal of Ophthalmology” This case report suggests that intralesional cidofovir may be a consideration for treating squamous cell carcinoma, as it showed a successful outcome without systemic toxicity, although surgical excision remains preferred.
43 citations
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August 2016 in “International Journal of Nanomedicine” This study found that a eupafolin nanoparticle delivery system improved water solubility and skin penetration, enhancing its antioxidant and anti-inflammatory effects against particulate matter-induced stress in skin cells.
60 citations
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December 2013 in “PLoS ONE” The researchers found that inhibiting soluble epoxide hydrolase, either genetically or pharmacologically, delayed the onset of chemically induced seizures related to GABA antagonism in experimental models.
October 2023 in “Facial Plastic Surgery” This review discusses combining follicular unit excision (FUE) and linear strip excision (LSE) donor harvesting methods to optimize graft yield while minimizing donor depletion, but provides no new clinical results.
80 citations
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April 2011 in “Plant physiology” This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.
The researchers reported that human foreskin fibroblasts isolated by enzyme digestion method proliferated faster and were purified more quickly than those isolated by the inverted tissue culture method; additionally, post-psoralen photoactivation therapy moderately repaired UVB-induced damage in these fibroblasts, suggesting potential clinical applications.
1 citations
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January 2025 in “Dermatology Practical & Conceptual” This review describes trichoscopy features of lichen planopilaris and frontal fibrosing alopecia, identifying distinct patterns that help differentiate the two conditions.
January 2026 in “Microsystems & Nanoengineering” This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.
38 citations
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February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
12 citations
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January 2016 in “Skin Appendage Disorders” This study reports an association between frontal fibrosing alopecia and lupus erythematosus, noting progressive alopecia in the frontotemporal hairline despite treatment with hydroxychloroquine.
2 citations
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January 2023 in “Uro” This study found that both a proprietary ultrahigh-pressure extract and a hexanic extract of saw palmetto showed comparable inhibition of 5α-reductase, suggesting similar potential for managing symptoms of benign prostatic hyperplasia.
June 1995 in “International Journal of Gynecology & Obstetrics” This article discusses immunohistochemical analysis of estrogen and progesterone receptors in endometrium and peritoneal endometriosis, introducing a new quantitative method, but reports no new experimental results.
April 2017 in “Journal of Investigative Dermatology” This study found that fisetin, a dietary flavonoid, significantly improved psoriasiform skin lesions in mice by promoting cell differentiation, inhibiting proliferation, and modulating inflammatory responses.
July 2020 in “CRS 2020 Virtual Annual Meeting” This study found that the newly developed microarray patches for intradermal delivery of finasteride showed high drug content and significantly improved skin deposition compared to existing methods.
August 2023 in “Cell Proliferation” This study observed that incorporating human follicle dermal papilla cells into fibrin microgels increased cell viability and the formation of hair follicle structures in in vitro skin cultures compared to traditional dermal papilla spheroids, suggesting a promising approach for hair follicle regeneration therapies.
11 citations
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January 2020 in “Engineered science” This study suggests that finasteride-loaded polyvinyl alcohol/chitosan microspheres could be a promising embolic agent for benign prostatic hyperplasia, showing effective occlusion and sustained drug release in preclinical models.
37 citations
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May 2007 in “International Journal of Pharmaceutics” The study concluded that poly(propylene carbonate maleate) microspheres effectively encapsulated finasteride, achieving a biphasic release with prolonged drug release over 5-6 weeks in vitro.
January 2025 in “JCEM Case Reports” This report describes a 27-year-old patient with Ehler-Danlos syndrome who also presented with hypophosphatasia and mastocytosis, and suggests enzyme replacement therapy might alleviate symptoms in such overlapping genetic conditions.