March 2021 in “Research Square (Research Square)” This study found that stress is likely the main cause of symmetrical alopecia in Formosan macaques, with higher stress hormone levels observed in affected individuals.
10 citations
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May 2010 in “Analytica Chimica Acta” This study reported the development of two highly sensitive ELISA assays to detect banned substances finasteride and dutasteride in human urine, offering better sensitivity than existing HPLC/MS/MS methods.
This study found that new methods for isolating human dermal papilla cells were more efficient than traditional methods, maintaining higher levels of specific markers and improving the cells' research potential.
This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
2 citations
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May 2021 in “Scientific Reports” In this study, researchers found that stress likely triggers symmetrical alopecia in Formosan macaques in Mt. Longevity, Taiwan, with higher stress hormone levels associated with the condition.
152 citations
,
December 2007 in “Gender Medicine” This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.
7 citations
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June 2021 in “Cell Proliferation” This study found that direct interactions between human dermal papilla cells and melanocytes under low oxygen conditions improved cell functions and could be important for hair regeneration efforts.
November 2025 in “Chemistry - An Asian Journal” This perspective reviews enzyme-instructed self-assembly (EISA) as a conceptual framework for supramolecular chemical biology, emphasizing its innovative role in developing adaptive biomaterials and synthetic cellular machines without providing new experimental results.
November 2024 in “Stem Cell Research & Therapy” A new method improves the isolation of hair follicle cells for better hair growth research.
5 citations
,
July 2000 in “Southern Medical Journal” This review discusses available treatments for androgenetic alopecia in men, like finasteride and 5% minoxidil, and notes that hair growth results are unpredictable and often driven by industry-sponsored studies.
41 citations
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June 2010 in “Anais Brasileiros de Dermatologia” This study found that isotretinoin is a safe and well-tolerated acne treatment, with common adverse effects like cheilitis manageable through symptomatic medication and no significant changes in lipid or liver enzyme levels.
26 citations
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March 2018 in “Dermatology and Therapy” This study found that conditioned media from epidermal progenitor cells improved skin aging signs in a clinical trial and protected fibroblasts from oxidative stress in vitro.
19 citations
,
September 2010 in “The American journal of pathology” This study demonstrated that elevated glucocorticoid levels in transgenic mice led to pancreatic exocrine cells transforming into hepatocyte-like cells, resulting in pancreatic dysfunction.
9 citations
,
March 2019 in “European Journal of Sport Science” This article discusses laboratory and physical markers that may help detect androgenic anabolic steroid abuse in athletes and reports no new primary research results.
30 citations
,
December 2017 in “Clinical, Cosmetic and Investigational Dermatology” This study found significant differences in hair density, non-vellus hair diameter, and percentage of miniaturized hair between normal women and those with female pattern hair loss, particularly in the midscalp and parietal areas.
November 2023 in “ACS Omega” This study reported that a novel cationic liposome formulation for delivering encapsulated Cas9 protein and sgRNA successfully decreased SRD5α2 mRNA expression by 29.7% in vitro, suggesting a potential alternative treatment option for conditions like prostate cancer and benign prostatic hyperplasia without current drug side effects.
April 2017 in “Al-Azhar Medical Journal” In this study conducted at Al-Azhar University Hospital, 60% of patients with localized alopecia areata responded to treatment with autologous platelet-rich plasma, with 89% of responders showing substantial improvement, suggesting PRP as an effective treatment option for this condition.
2 citations
,
January 2023 in “BioMed Research International” This review discusses the potential of mesenchymal stromal cell secretome therapies for facial nerve palsy, emphasizing their standardization advantages over cell transplantation, but provides no new clinical results.
1 citations
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January 2024 in “Journal of clinical medicine” This literature review highlights the changing epidemiology of tinea capitis due to global migration and underscores the importance of early recognition and treatment of atypical variants in immunocompetent children to minimize prolonged systemic antifungal therapy and prevent adverse events, especially regarding liver health.
January 2026 in “Industrial Crops and Products” In this study, oral administration of ginsenoside Rf from Panax ginseng promoted hair regrowth and increased hair thickness in a mouse model of androgenetic alopecia by enhancing androgen receptor degradation, highlighting its potential for cosmetic and functional food applications.
6 citations
,
September 2012 in “Clinical Interventions in Aging” This study found that honokiol inhibits enzymes related to testosterone degradation in vitro, suggesting its potential as a lead compound for developing antiaging bioactive ingredients for men.
30 citations
,
October 2020 in “Nature Communications” This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.
73 citations
,
April 2017 in “Scientific Reports” In this study, nitrogen starvation in Chlorella sp. FC2 IITG led to increased lipid accumulation by altering the expression of enzymes involved in various metabolic pathways, suggesting potential for genetic engineering of microalgae.
35 citations
,
January 2002 in “Scandinavian Journal of Urology and Nephrology” This study found that finasteride treatment decreased VEGF expression in the prostate tissue of patients with benign prostatic hyperplasia, although it did not affect vascular density or serum VEGF levels.
24 citations
,
January 2015 in “Annals of Dermatology” In this study, herbal extracts commonly used in traditional medicine were observed to significantly increase the proliferation of human dermal papilla cells, suggesting potential as alternative therapies for enhancing hair growth.
20 citations
,
March 2013 in “Journal of Lipid Research” This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.
13 citations
,
January 2020 in “Neuroscience” This study found that finasteride impaired object recognition memory and altered hippocampal dendritic structures in male 3xTg-AD mice, suggesting potential sex differences in Alzheimer's disease pathology.
12 citations
,
January 2018 in “Journal of Drug Delivery Science and Technology” This study developed solid lipid nanoparticles for effective delivery of shRNA-encoding plasmids, showing reduced 5α-reductase levels in DU-145 cells without significant cytotoxicity.
6 citations
,
August 2024 in “Biomacromolecules” This study introduces a novel in vitro model for clubfoot fibrosis to enable high-throughput drug screening and found that while the model increased collagen deposition, the antifibrotic drug minoxidil effectively inhibited the expression of collagen cross-linking enzymes.
5 citations
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July 2014 in “Acta Crystallographica Section D-biological Crystallography” This study reports that mutations in human L-PGDS affect the entrance and exit of ligands in its binding cavity, suggesting these residues play a role in ligand interaction processes.