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A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.

Thyroid function affects skin health, with a complex interaction between the two.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Pannexin 3 is important for bone formation and the development of bone cells.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Ozone therapy might improve cancer treatment and reduce its side effects.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.