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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.

Testosterone therapy increases bone density in older men with low testosterone levels.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Androgens prevent hair growth by changing Wnt signals in cells.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

FLRG and follistatin have different roles in wound healing.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.