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Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

This review summarizes existing knowledge on androgen receptor activity in breast cancer and reports no new clinical findings, with emphasis on therapies targeting androgen signaling in specific BC subtypes.

This study found that a 6-month treatment with either metformin or rosiglitazone significantly improved endothelial function in young women with PCOS without any one drug being superior.

This review discusses the potential of targeting glucocorticoid action as a treatment strategy for obesity and type-2 diabetes, highlighting promising animal study results but reports no new clinical findings.

This review discusses the use of antimüllerian hormone as a marker of ovarian reserve in infertility diagnosis and treatment, noting it reflects oocyte quantity but not health or pregnancy likelihood.

In this study, reduced androgen receptor gene methylation and shorter CAG repeats in children with premature pubarche may lead to increased hair follicle sensitivity to steroid hormones, potentially causing early pubic hair development.

This study defined menstrual phase-specific reference intervals for circulating androgen levels in young women, highlighting that anovulatory females showed higher androgen, LH, and FSH levels compared to ovulatory females.

In this study of reproductive-aged women in Tehran, idiopathic hirsutism and polycystic ovary syndrome were reported to be prevalent, with rates influenced by the screening methods used.

This study found that both high-dose and low-dose finasteride significantly reduced hirsutism scores in women after 12 months, with the lower dose being safe and cost-effective.

This study found that miRNA expression profiles in follicular fluid are altered in women with PCOS, with certain miRNAs potentially useful for distinguishing patient subtypes and contributing to understanding PCOS heterogeneity.

This review offers evidence-based recommendations for diagnosing and treating female pattern hair loss, emphasizing clinical assessment and starting treatment with minoxidil, while noting that measurement of certain hormones and vitamins is optional.

This review discusses the presence of the StAR protein in 17 non-classical steroidogenic tissues, suggesting that advanced detection methods are needed for a complete understanding of its functions in these tissues.

In this study, the authors concluded that COVID-19 may not cause direct long-term harm to testicular function, but temporary indirect effects could occur, suggesting a possible delay in pursuing parenthood post-recovery.

In this study, higher expression levels of aromatase and steroidogenic acute regulatory protein were correlated with increased estrogen synthesis and fewer hair follicles in human skin, suggesting a link to elastic fiber formation and hair growth.

In this study, ketoconazole treatment improved acne in all women and reduced hirsutism in some, but it caused several side effects and requires careful monitoring.

This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.

This paper discusses mechanisms by which various chemicals disrupt male sexual differentiation, concluding that mixture risk assessments should include a broader set of compounds beyond phthalates to address cumulative reproductive health risks.

In this study, treatment with insulin sensitizers significantly increased adipose tissue GLUT4 mRNA expression and improved insulin resistance, menstrual patterns, and androgen profiles in PCOS patients, with rosiglitazone being more effective than metformin.

This review discusses the clinical use of anti-androgen medications and highlights emerging evidence supporting plant-derived anti-androgens like spearmint tea for managing PCOS, but reports no new clinical results.

This study estimates the prevalence of hyperandrogenic states in late adolescent and young females, revealing that these disorders often begin at a young age.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

This study in Italy found that APS-1, a rare disorder, is associated with various AIRE gene mutations and most individuals have autoantibodies such as IFNωAbs, which are markers of the condition.

This article reviews androgen excess and cardiometabolic risks in women, highlighting increased cardiovascular disease risk in those with polycystic ovary syndrome, but reports no new clinical results.

This article discusses the challenges in diagnosing non-classical congenital adrenal hyperplasia and emphasizes personalized treatment approaches, reporting no new clinical results.

The authors concluded that dermal white adipose tissue, influenced by factors like light irradiation, plays a significant role in modulating hair follicle cycles and could be targeted for hair growth treatments.

In this study, women with polycystic ovary syndrome had significantly higher lipocalin-2 levels compared to controls, suggesting it may be a useful marker for insulin resistance in this population.

This study found that Indian women with PCOS following a vegetarian diet had higher pro-inflammatory and lower anti-inflammatory marker levels compared to age and BMI-matched non-vegetarian counterparts.

This study indicates that the normal human prostate is not a major contributor to circulating blood DHT concentrations in androgen-deficient patients receiving testosterone replacement therapy.

In this study, daughters of women with PCOS and control daughters showed no significant differences in metabolic and hormonal parameters, but more PCOS daughters exhibited hirsutism at advanced pubertal stages.

This study reported that both drospirenone and chlormadinone acetate oral contraceptives had similar beneficial effects on clinical, metabolic, and hormonal parameters in women with polycystic ovary syndrome over six months.