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The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Some alternative treatments for hair loss might work, but more research is needed.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Melatonin solution helps treat hair loss in men and women.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Using steroids can increase the risk of heart problems.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

A male with aromatase deficiency improved bone health with estradiol treatment.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Early diagnosis and treatment of TPP can prevent complications.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

PRP treatment improves hair density and thickness for alopecia, but needs more research.

Sex hormones affect brain injury differently in males and females.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Caffeine applied to the scalp can protect hair follicles from UV damage.