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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

A male with aromatase deficiency improved bone health with estradiol treatment.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Early diagnosis and treatment of TPP can prevent complications.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

PRP treatment improves hair density and thickness for alopecia, but needs more research.

Sex hormones affect brain injury differently in males and females.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Caffeine applied to the scalp can protect hair follicles from UV damage.

A natural steroid in the body may protect against eye damage in glaucoma.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

CIP/KIP proteins help stop cell division and support hair growth.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.