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Stress can worsen skin conditions by affecting hormone levels and immune response.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Metformin is less effective in men with early-onset hair loss.

Early diagnosis and hormone therapy can significantly improve outcomes for post-partum pituitary insufficiency in resource-limited settings.

Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.

The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Finasteride doesn't affect hormone levels in normal men.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

Lithium can treat bipolar disorder but may cause hair loss and other hair problems.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Finasteride reduces hair growth and is safe for women with excessive hair.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Finasteride caused enlarged breast tissue in a 62-year-old man.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

A woman with low thyroid function did not lose her hair during chemotherapy, possibly because her hair follicles were less affected by the treatment.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Quercetin may help with PCOS symptoms, but more research is needed.