research Approach to the Patient: Diagnostic Challenges in the Workup for Polycystic Ovary Syndrome
Diagnosing PCOS is challenging due to its complex and varied symptoms.
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research Pediatric Androgenetic Alopecia: A Review
Early diagnosis and treatment, like topical minoxidil, can prevent hair loss in children.
research Gender-Specific Risk Factors for Androgenetic Alopecia in the Korean General Population: Associations with Medical Comorbidities and General Health Behaviors
AGA risk factors include age, smoking, hypertension for men, and age, dyslipidemia for women; lifestyle changes may help prevention.
research From Basal Cell Carcinoma Morphogenesis to Alopecia Induced by Hedgehog Inhibitors: Connecting the Dots
The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
research Androgens and Hair Growth
Androgens can both increase and decrease hair growth in different parts of the body.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
research Shedding: How to Manage a Common Cause of Hair Loss
Manage hair shedding by identifying triggers, possibly using supplements or medications, and tracking with a health calendar.
research Assessment of the Obese Patient
Doctors need to be better prepared to assess and treat obesity in patients.
research Four-Amino Acid Segment in Steroid 5 Alpha-Reductase 1 Confers Sensitivity to Finasteride, a Competitive Inhibitor
Four-amino acid part makes enzyme sensitive to finasteride.
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research Localized Alopecia and Suppression of Hypothalamic-Pituitary-Adrenal Axis in Dogs Following Treatment with Difluprednate 0.05% Ophthalmic Emulsion
Long-term use of difluprednate eye drops in dogs can lead to hair loss and hormone imbalance.
research The Clinical Management of Testosterone Replacement Therapy in Postmenopausal Women with Hypoactive Sexual Desire Disorder: A Review
Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.
research Prevalence of Hepatic Steatosis in Women with Polycystic Ovary Syndrome
Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.
research Drugs Affecting Blood Coagulation, Fibrinolysis, and Hemostasis
Some blood-thinning medications can increase the risk of bleeding, and certain factors like genetics and other health conditions affect their safety and effectiveness.
research The Clinical Evaluation of Hirsutism
Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.
research Proceedings of the Ninth World Congress for Hair Research 2015
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Cutaneous Markers of Disorders Affecting Adult Horses
Skin and hair changes in horses can indicate serious diseases, and recognizing these signs is important for treatment and management.
research Intracrine Androgen Biosynthesis, Metabolism, and Action Revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Spatiotemporal Expression, Distribution, and Processing of POMC and POMC-Derived Peptides in Murine Skin
POMC-derived peptides are important for skin functions like immune response and stress management.
research p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis
The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
research Recent Advances on Skin-Resident Stem/Progenitor Cell Functions in Skin Regeneration, Aging, and Cancers and Novel Anti-Aging and Cancer Therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Nudging Hair Shedding by Antidandruff Shampoos: A Comparison of 1% Ketoconazole, 1% Piroctone Olamine, and 1% Zinc Pyrithione Formulations
All three shampoos reduced dandruff and hair loss, but ketoconazole and piroctone olamine also made hair thicker.
research PRC2 Preserves Intestinal Progenitors and Restricts Secretory Lineage Commitment
PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
research Toxoplasma Gondii Infection and Testosterone Alteration: A Systematic Review and Meta-Analyses
Toxoplasma gondii infection may increase testosterone levels in males.
research An Integrative View of Mammalian Seasonal Neuroendocrinology
The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research Non-Biologic Immunosuppressive Drugs for Inflammatory and Autoimmune Skin Diseases
Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.
research Sebum Production: Analysis, Impact, and Measurement Methods
Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.
research Biotechnological Applications of Mushrooms Under the Water-Energy-Food Nexus: Crucial Aspects and Prospects from Farm to Pharmacy
Mushrooms offer benefits for food, energy, and water security, and have potential uses in health and environmental applications.
research Hormonal, Medical, and Nonsurgical Aspects of Gender Affirmation
The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.