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      The Hair Follicle: A Paradoxical Androgen Target Organ

      research The Hair Follicle: A Paradoxical Androgen Target Organ

      66 citations , January 2000 in “Hormone Research in Paediatrics”
      This study suggests that the paradoxical effects of androgens on hair growth are due to differential gene expression in hair follicles, possibly established during embryogenesis.
      Microneedles as the Technique of Drug Delivery Enhancement in Diverse Organs and Tissues

      research Microneedles as the technique of drug delivery enhancement in diverse organs and tissues

      140 citations , December 2017 in “Journal of Controlled Release”
      This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.
      Hair Follicle Culture

      research Hair Follicle Culture

      January 2012 in “Methods in pharmacology and toxicology”
      This review discusses the use of cultured hair follicles for studying hair growth regulation and reports the challenge of modeling the entire hair cycle in vitro.
      Frontiers in the Neuroendocrine Controls of Hair Growth

      research Frontiers in the (Neuro-)endocrine Controls of Hair Growth

      22 citations , November 2007 in “Journal of Investigative Dermatology Symposium Proceedings”
      This presentation reviews recent discoveries about signaling mechanisms in hair follicles and their potential influence on hair cycle control and melanogenesis, without presenting new experimental results.
      Androgens in Women: Role in Androgen-Mediated Cutaneous Disorders

      research Androgens in women

      56 citations , October 2018 in “Journal of The American Academy of Dermatology”
      This review discusses the role of androgens in women's skin-related conditions like acne, hirsutism, and female pattern hair loss, noting the lack of dermatology guidelines for when to pursue endocrinologic evaluation.
      Diversification and Specialization of Touch Receptors in Skin

      research Diversification and Specialization of Touch Receptors in Skin

      81 citations , June 2014 in “Cold Spring Harbor perspectives in medicine”
      This article discusses recent advances in understanding the mechanisms of tactile end organs in the epidermis and hair follicles from studies of mouse hairy skin, but it reports no new clinical results.

      research Fibroblasts: Origins, definitions, and functions in health and disease

      488 citations , July 2021 in “Cell”
      This review discusses the development, lineages, functions, and roles of fibroblasts in fibrosis across four organs, highlighting their capabilities in tissue repair and contributions to fibrotic disorders when aberrantly activated, but it reports no new experimental findings.
      Anatomy and Physiology of the Skin

      research Anatomy and Physiology of the Skin

      277 citations , July 2011 in “Journal of the Dermatology Nurses’ Association”
      The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
      Fetal Skin Wound Healing

      research Chapter 6 Fetal Skin Wound Healing

      89 citations , January 2009 in “Advances in Clinical Chemistry”
      This review discusses the differences in wound healing between fetal and adult skin, highlighting the potential to uncover genes for scarless repair that could improve adult wound healing.
      Stem Cells in the Body

      research Stem Cells in the Body

      November 2017
      This chapter reviews the presence and roles of stem cells in various body systems, focusing on their lifelong function in animals and humans, and reports no new experimental findings.
      The Hair Follicle as a Dynamic Mini-Organ

      research The Hair Follicle as a Dynamic Miniorgan

      759 citations , February 2009 in “Current Biology”
      This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.
      Functional Mapping of the Mouse Hairless Gene Promoter Region

      research Functional mapping of the mouse hairless gene promoter region

      January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”
      This study identified a new cis-regulatory element in the mouse Hr gene that influences its expression in skin and brain cells, highlighting a complex molecular network involved in hair follicle formation.
      Plucked Human Hair Shafts and Biomolecular Medical Research

      research Plucked Human Hair Shafts and Biomolecular Medical Research

      8 citations , January 2013 in “˜The œscientific world journal/TheScientificWorldjournal”
      This review explores the potential use of plucked hair follicles in regenerative medicine and diagnostics but presents no new research findings.
      Cutaneous Signals of Immune System Disease

      research Cutaneous signals of immune system disease

      May 1991 in “Current problems in dermatology”
      This article reviews the relationship between the skin and the immune system and discusses how skin manifestations can indicate immunodeficiencies but reports no new research findings.

      research Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system

      February 2026 in “Biochemical and Biophysical Research Communications”
      This study identifies a specific cell population, PDGFRα+/Sca1+/CD34+ mesenchymal cells, which play a crucial role in regenerating hair follicles by promoting the downgrowth phase of the hair cycle, offering insights into organ morphogenesis and stem cell niches essential for adult hair regeneration.
      The Role of Fgf20 in Establishing the Hair Follicle Dermal Condensate

      research 1362 The role of Fgf20 in establishing the hair follicle dermal condensate

      April 2018 in “Journal of Investigative Dermatology”
      This study found that Fgf20 signaling facilitates fibroblast migration and influences dermal condensate cell development during hair follicle morphogenesis by supporting cellular activities such as cell cycle exit and specific cell shape adoption.
      Whole Neonatal Cochlear Explants as an In Vitro Model

      research Whole Neonatal Cochlear Explants as an In vitro Model

      1 citations , July 2023 in “Journal of visualized experiments”
      This study presents an improved protocol for isolating and culturing whole neonatal cochlear explants, enabling detailed analysis of hair cells and spiral ganglion neuron cells while simplifying culture steps without sacrificing explant quality, and was successfully tested on mice and rat cochleas.

      research Phenol in dermatology: updated evidence on efficacy and safety

      August 2025 in “Anais Brasileiros de Dermatologia”
      This review details phenol's dermatological uses and underscores its potent skin rejuvenation effects but emphasizes the need for caution due to risks of serious complications, including cardiac arrhythmias and organ failure, particularly with improper use or large-area applications.
      Hair Follicles and Associated Glands as Androgen Targets

      research 8 Hair follicles and associated glands as androgen targets

      53 citations , May 1986 in “Clinics in endocrinology and metabolism”
      This review discusses the influence of androgens on hair and sebaceous growth, emphasizing that response may depend more on peripheral sensitivity than on hormone levels; it reports no new empirical results.
      Stem Cell Translation And Bioethics

      research stem cell translation and bioethics

      April 2012 in “Annals of Neurosciences”
      This article discusses the development of the regenerative medicine field based on stem cells' capacity for in vitro differentiation, rather than actual organ or tissue regeneration.
      The Blastema and Epimorphic Regeneration in Mammals

      research The blastema and epimorphic regeneration in mammals

      85 citations , December 2017 in “Developmental Biology”
      This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.