October 1997 in “Dermatologic Surgery” The Epilight Hair Removal System is effective for temporary hair removal with few side effects, but more research is needed to confirm its safety and long-term results.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that conditional deletion of Mof in mice resulted in severe defects in skin development, including compromised epidermal differentiation and hair growth, leading to perinatal lethality.
October 2021 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study found that applying a cosmetic active ingredient improved the Young's modulus of chemically damaged human hair fibers, suggesting enhanced mechanical properties compared to untreated fibers.
2 citations
,
February 2022 in “Human Gene Therapy” This study found that upregulated miR-149 restricted hair follicle stem cell differentiation and hair growth by inhibiting the MAPK1/ERK2 pathway, which affects FGF2 and c-MYC expression.
July 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review suggests that excessive facial photoprotection could play a role in frontal fibrosing alopecia through a disturbance in immunological balance via the aryl hydrocarbon receptor-kynurenine pathway.
January 2025 in “Open Veterinary Journal” This case series reports that electrochemotherapy with intravenous bleomycin effectively resolved cutaneous mast cell tumors in four cats, showing no tumor recurrence during follow-up, except for new lesions in one cat, and minimal local toxicity.
4 citations
,
August 2015 in “Journal of Cosmetic Dermatology” This study found that UVA blocker-containing sunscreens instantly reduced follicular fluorescence due to porphyrins in facial skin, with the effect lasting for a few hours, influenced by sunscreen amount and formulation.
2 citations
,
March 2025 in “PNAS Nexus” In this study, researchers used Raman spectroscopy to identify melanin-specific features in mouse hair as potential biomarkers for gamma-radiation exposure, achieving a sensitivity of 88% and specificity of 83%, with classification accuracy declining over time beyond 7 days post-irradiation.
August 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study found significant hair growth improvement with microneedling radiofrequency treatment in most patients with patterned hair loss, with minimal short-term adverse effects.
This study suggests that targeting the activation of transit-amplifying cell-derived progenitor cells may help prevent hair loss from chemotherapy and radiotherapy by promoting hair follicle regeneration.
April 2023 in “Journal of Investigative Dermatology” This pilot study suggests that topical melatonin may protect hair follicle stem cells from paclitaxel-induced damage, potentially preventing chemotherapy-induced alopecia and enhancing the effects of scalp cooling caps.
In this pilot study, researchers found that ex vivo treatment with topical melatonin reduced chemotherapy-induced apoptosis and DNA damage in hair follicle stem cells of human scalp cultures, suggesting melatonin's potential as a protective agent against taxane-induced permanent hair loss.
This study developed a new analytical method to identify a wide range of endocrine disrupting compounds in full-term amniotic fluid, revealing diverse substances with potential endocrine activity.
August 2007 in “Microscopy and Microanalysis” Hair fibers break by cuticle cell slipping, shape changing, cuticle fraying, and surface cracking when stretched under specific conditions.
November 2025 in “Journal of Investigative Dermatology” Radiation-induced hair loss may be caused by hair growth stopping and inflammation in blood vessels.
122 citations
,
July 2005 in “The FASEB journal” This study found that hair follicles in both mice and humans may serve as an important site for melatonin synthesis and signaling, potentially influencing hair cycle regulation by modulating keratinocyte apoptosis.
3 citations
,
January 2010 April 2026 in “Dermatological Reviews” In this study, both radiofrequency microneedling and ultrasound treatments with a plant-based secretory factor hair serum enhanced hair and scalp health in subjects with androgenetic alopecia, with ultrasound showing more pronounced improvements in hair appearance, density, and color.
25 citations
,
April 2008 in “Clinical and experimental dermatology” This case series describes Erythromelanosis follicularis faciei et colli in five Indian patients, suggesting it may be more common than currently reported.
41 citations
,
December 2019 in “Science Translational Medicine” This study found that EGFR-targeted cancer therapy can cause skin toxicities by disrupting epidermal signaling, allowing microbiota invasion and inflammation, but identified a potential treatment approach using FGF7 or SOS expression to restore barrier integrity.
11 citations
,
August 2006 in “Cell Biology International” This study found that endothelin-1 increases adhesion and chemotaxis of amelanotic melanocytes on fibronectin, laminin, and collagen IV, potentially through changes in the actin cytoskeleton.
43 citations
,
August 2016 in “International Journal of Nanomedicine” This study found that a eupafolin nanoparticle delivery system improved water solubility and skin penetration, enhancing its antioxidant and anti-inflammatory effects against particulate matter-induced stress in skin cells.
June 2008 in “Experimental dermatology” This research found that melatonin plays a protective and modulatory role in skin biology, reducing UV damage and chemotherapy-induced hair follicle cell harm in human organ culture models.
7 citations
,
November 1997 in “Reproduction Fertility and Development” In this study, subcutaneous injections of murine epidermal growth factor in marsupial pouch young inhibited the formation of hair follicles and associated structures, altering normal follicle development.
May 2025 in “Drug Delivery and Translational Research”
February 2010 in “Journal of The American Academy of Dermatology” The document concludes that using gadolinium-based contrast agents during MRI can be linked to Nephrogenic Systemic Fibrosis in patients with severe kidney disease.
19 citations
,
April 2020 in “Oxidative Medicine and Cellular Longevity” This study provides evidence that Fernblock® upregulates antioxidant pathways in cultured keratinocytes, potentially protecting against damage from fine pollutant particles.
82 citations
,
March 2013 in “PLoS ONE” In this study, vemurafenib was associated with a wide range of cutaneous side effects in patients with advanced melanoma, including photosensitivity and various skin and hair changes, necessitating regular dermatological management.
23 citations
,
December 2001 in “Lasers in Surgery and Medicine” This article discusses the extended theory of selective photothermolysis and does not report new clinical results; the authors explore potential applications in hair removal techniques.