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The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Androgens may block hair growth signals, targeting this could treat hair loss.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

PI3K/Akt pathway is crucial for hair growth and regeneration.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

Boosting β-catenin signaling in certain skin cells can enhance hair growth.

Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.

Stem cell therapy is a promising approach for hair regrowth despite potential side effects.

The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.

Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.

Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.

Collagen and TGF-β2 help maintain hair cell shape and youthfulness.

XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.

Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.

The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.

Thymosin β4 helps increase hair growth in Cashmere goats.

Allium hookeri extract may help promote hair growth and protect cells from damage.

The new microwell device helps grow more hair stem cells that can regenerate hair.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.