9 citations,
May 2012 in “PLOS ONE” ILK is essential for skin development, pigmentation, and healing.
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8 citations,
March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
8 citations,
February 2014 in “Stem cells translational medicine” Modified stem cells that overexpress a specific protein can improve hair growth and reduce hair abnormalities in mice.
8 citations,
October 1996 in “JAMA” The document suggests a young mother use effective contraception like the Copper-T IUD while considering her health and the need for STD prevention.
8 citations,
January 1996 in “Springer eBooks” Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
7 citations,
August 2022 in “Nature communications” A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
7 citations,
May 2019 in “European Journal of Human Genetics” BMP4-related anomalies can cause a wide range of eye, brain, and hand/foot problems, and new cases show this variability.
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October 2018 in “BMC genomics” Key genes can rewire networks, changing skin appendage types.
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January 2018 in “Reproduction” Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
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April 2017 in “Health Economics, Policy and Law” The document suggests reevaluating the patent system to ensure public benefits from pharmaceutical privileges and to encourage more significant innovations.
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October 1985 in “Genetics Research” Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.
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May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
6 citations,
April 2010 in “Cellular Reprogramming” Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
5 citations,
January 2022 in “Scientific reports” The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
5 citations,
January 2021 in “iScience” Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
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November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
Selenium can be toxic to animals, causing serious health issues, especially in horses.
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January 2019 in “International journal of molecular sciences” Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.
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January 2018 in “Elsevier eBooks” Hormones are crucial for regulating body functions and imbalances can lead to health issues.
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March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
3 citations,
October 2022 in “PloS one” Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.
3 citations,
January 2019 in “Advances in stem cells and their niches” Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
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August 2023 in “Development” Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
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May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
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April 2021 in “International Journal of Molecular Sciences” The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
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August 2020 in “Scientific reports” Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
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May 2020 in “Journal of visualized experiments” Controlled light treatment in mouse skin speeds up healing and hair growth.
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January 2019 in “Medizinische Genetik” The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.