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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Researchers created human hair follicles using a new method that could help treat hair loss.

Higher doses of cranial irradiation are linked to permanent hair loss.

Women with PCOS are more likely to suffer from depression, anxiety, and stress.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

AR polyglycine repeat doesn't cause baldness.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

People with lichen planus have higher bad cholesterol and lower good cholesterol, increasing their risk for heart disease.

Finasteride effectively increases hair growth in men with AGA, works better for those over 30, and may cause some side effects.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.

Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

Late puberty may slightly lower prostate cancer risk, baldness is not linked to overall risk but less so with aggressive types, ibuprofen use may increase risk, and vitamins show no effect on risk.

Enzyme purified and characterized for minoxidil sulphation in rat liver.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Rosemary's antioxidant content changes with the climate and season.