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Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.

Using iontophoresis on minoxidil sulphate-loaded chitosan nanoparticles increases drug release but reduces its targeting to hair follicles.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Certain drugs that block specific enzymes can help treat prostate diseases.

Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.

CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.

The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

The conclusion is that lifestyle changes and weight loss are first-line treatments for infertility due to anovulation, with various medications and assisted reproductive technologies as additional options.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.