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The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Androgens can cause hair growth in some areas and hair loss on the scalp.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.