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Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

Bone marrow and umbilical cord stem cells can help grow new hair.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

Severe COVID-19 may cause hair loss, and doctors recommend supplements and topical treatments to manage it.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Minoxidil use during pregnancy may cause fetal harm.

A patient had skin tissue death at the hair removal site after a hair transplant, which was treated with surgery.

WNT10A mutations cause varied symptoms in patients with odonto-onycho-dermal dysplasia.

Minoxidil solution safely and effectively treats hair loss.

Minoxidil helps treat severe high blood pressure.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Using stem cells from fat tissue can significantly improve wound healing in dogs.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.