Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study concluded that early-stage tissue-engineered skin substitutes, developed using skin progenitor cells, had a better graft efficiency and supported hair follicle formation, which may improve wound healing outcomes.

This review discusses the potential of mesenchymal stem cells from human periapical cysts for regenerative medicine, highlighting their easy accessibility and valuable regenerative properties, but reports no new clinical findings.

This study reports that tissue-engineered skin using ES cell-derived epidermal stem cells and collagen sponge successfully healed full thickness skin defects in mice, forming epidermis and structures resembling glands and hair follicles.

This review discusses new developments in understanding the structure and properties of keratin fiber cell membrane complexes, without reporting new experimental results.

This study explores ear pinna development in mice and reports that elastic cartilage formation is disrupted in a short ear mutant, correlating with increased adult adipocytes and impaired chondrogenesis.

This study found that disrupting Sox21 in developing teeth leads to severe enamel hypoplasia, regional osteoporosis, and abnormal hair formation, with impaired dental epithelial differentiation and regulation of hair follicle cell fate.

This study found that the deletion of Med1 in dental epithelia causes a shift from dental to hair tissue development, suggesting the importance of Med1 in maintaining tissue-specific lineage.

This review summarizes the characteristics of the peri-malignant melanoma stroma, indicating its potential role in early dermal metastatic migration and increased metastasis risk.

Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.

This study found that the Meibomian gland shares structural and cytokeratin composition similarities with hair follicles, and plays a role in hyper-keratinisation observed in obstructive Meibomian gland dysfunction.

This review examines the complex role of the Ectodysplasin-A pathway in skeletal morphogenesis, emphasizing its interaction with other key signaling pathways, and reports no new experimental findings.

This study found that overexpression of antizyme in MEK-activated transgenic mice reduced skin tumor development and restored normal differentiation of keratinocyte progenitor cells, highlighting the role of polyamines in keratinocyte biology.

This review discusses the cellular and molecular changes involved in cutaneous wound re-epithelialization and EMT, highlighting their similarities and differences, but reports no new clinical results.

This study analyzes the fine structure and protein distribution in monotreme hairs, finding similarities with other mammals and detailing unique immunocytochemical features in their inner root sheaths.

In this study, researchers explored ear pinna development in two rodent species and identified that BMP5 plays a crucial role in chondroblast proliferation but not in their initial specification, with implications for understanding tissue differentiation and potential impacts on reconstructive surgery.

This review discusses the regenerative processes of lizard tails, particularly focusing on the diversity in blastema development across different species, and reports no new findings.

This study introduces the term "hair matrix cyst" for a cyst with both pilomatricoma and epidermal cyst characteristics, highlighting its potential for misdiagnosis among similar skin conditions.

This review discusses recent advances in developmental tissue engineering for regenerating ectodermal appendages like teeth and glands, emphasizing biomaterial selection and cell culture strategies, but reports no new experimental results.

This paper explores the relationship between the dermal extracellular matrix and cutaneous malignant melanoma, suggesting that ECM involvement may play a key role in the cancer's growth, invasiveness, and initial metastasis.

In this case study, a 51-year-old Japanese man was diagnosed with desmoplastic trichoepithelioma after histological examination of surgically excised facial plaques.

This review discusses key signaling pathways involved in tooth formation, highlighting their role in understanding tooth regeneration and potential therapies for dental abnormalities.

This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.

This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.

In this study, the authors reported that combining PMSC-secretome and Wnt10b in a GelMA hydrogel scaffold promoted effective hair follicle biofabrication and hair growth in a small in vivo experiment. They emphasized the need for larger studies to confirm these results.

This review discusses the complex role of the EDA pathway in vertebrate skeletal development, emphasizing its interaction with other morphogenic pathways to influence skeletal diversity, but reports no new experimental results.

This study analyzed the cornified envelope of epidermal proteins, finding keratins dominate, which may help explain the minimal impact of deleting genes for single envelope components in congenital ichthyosis.

This study observed two cases of pigmented epithelioid melanocytoma suggesting potential differing origins: one from a hair follicle's outer root sheath and another from an intradermal nevus.

This study found that mechanical and chemical interactions in skin organoids are crucial for initiating mesenchymal-epithelial interactions necessary for hair follicle regeneration.

This article reviews the similarities in early development processes of hair follicles, teeth, and mammary glands and reports no new experimental findings.