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60-90 / 1000+ resultsresearch Ultrastructural Resemblance of Basal Cell Epithelioma to Primary Epithelial Germ
This study found that basal cell epithelioma resembles fetal primary epithelial germ based on specific cellular characteristics.
research The cellular basis of mechanosensory Merkel-cell innervation during development
This study identified key cells and pathways needed for the development of touch receptor patterns in mouse skin, notably that certain keratinocytes are crucial for innervation patterns, while Merkel cells and BMP signaling have distinct roles.
research Generation of bioengineered feather buds on a reconstructed chick skin from dissociated epithelial and mesenchymal cells
This study developed a bioengineering method to reconstruct embryonic dorsal skin from dissociated chick skin cells, allowing feather buds to form and grow in vitro, influenced by epithelial-mesenchymal interactions.
research Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile
This study found that mesenchymal cells from different organs exhibit substantial heterogeneity, with thymic mesenchymal cells particularly adapted for interacting with epithelial and hematolymphoid cells in high-apoptosis environments.
research Three-dimensional microanatomy of mechanoreceptors and their possible mechanism of sensory transduction.
This study proposes that the terminal tuft structure in sensory nerve endings, involving Schwann cell processes and axon fingers, potentially plays a role in mechano-electric transduction in rats.
research Human retinal secretome: A cross-link between mesenchymal and retinal cells
This review discusses the interaction between mesenchymal stem cell secretomes and retinal cell secretomes, suggesting their potential in experimental therapies to protect and regenerate retinal tissue.
research Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing via creating a fetal-like niche
In a study using a rat model, researchers developed injectable hydrogels from antler reserve mesenchyme which enhanced regenerative healing of full-thickness cutaneous wounds by creating a fetal-like niche that increased stem cell presence and modulated gene expression related to wound healing.
research 626 Early-stage bilayer tissue-engineered skin substitute formed by adult skin progenitor cells produces an improved skin structure in vivo
Early-stage skin substitutes improve wound healing and skin structure.
research Histologische Untersuchungen an der bindegewebigen Wurzelscheide des Sinushaarfollikels bei der Katze: das Sinuskissen
This study examines the structure of the "sinuskissen" in cat hair follicles, revealing it as a loose connective tissue susceptible to changes in aqueous flow, and describes its variable three-dimensional shapes.
research Embryonic keratinization in vertebrates in relation to land colonization
This study explains how the development of keratin-associated proteins in embryonic epidermis is crucial for forming protective barriers in vertebrates, enabling them to adapt to terrestrial environments.
research Interrogating the integument: the role of the epidermis in hair induction
This commentary discusses the role of the epidermis in hair follicle induction and reports no new research findings.
research 0873 Modeling junctional epidermolysis bullosa using tissue-engineered skin substitutes
Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.
research Characterization of a mouse Scube3 reporter line
Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
research A new tool for conditional gene manipulation in a subset of keratin‐expressing epithelia
This study reported that a Megsin-Cre transgene enables genetic manipulation primarily in skin, forestomach, and esophagus tissues, offering a new tool for studying development and diseases in these areas.
research Cornified Epithelial Teeth of Jawless Vertebrates Contain Proteins Similar to Keratin-Associated Proteins of Mammalian Skin Appendages
This study reports that KRTAP-like proteins, which resemble keratin-associated proteins found in mammals, are also present in the cornified teeth of various lamprey species, suggesting these proteins may serve similar functions in skin appendages across different vertebrates despite independent evolutionary origins.
research Harnessing mesenchymal aggregation for engineered organ‐level regeneration: Recent progress and perspective
In this review, it is discussed how mesenchymal stem cell aggregation plays a crucial role in organ development and has potential applications in organ regeneration through tissue engineering.
research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species
This study found that CD90+ stem cells with fibroblast-like morphology are present in the lower part of the anagen hair follicle in dogs.
research 線維芽細胞凝集塊形成による幹細胞形成機構の解明
This study found that cell spheres formed from mesenchymal cells in newborn mouse skin showed increased expression of genes associated with hair follicle regeneration, though marker distribution varied and requires further investigation.
research Tenascin-C expressing touch dome keratinocytes exhibit characteristics of all epidermal lineages
In this study, researchers identified Tenascin-C as a marker for touch dome keratinocytes, which maintain themselves and can develop into Merkel cells following injury, showing they share molecular traits with various epidermal keratinocytes.
research Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages
This review examines the role of stem cells and their niches in continuously growing ectodermal organs like teeth, hair, and claws, providing insights from mouse models without presenting new research findings.
research 5a Trichoepithelioma
This article reviews confocal microscopy findings in trichoepithelioma and desmoplastic trichoepithelioma, noting similarities with histological features, but it provides no new clinical results.
research A Chemically Defined Culture for Tooth Reconstitution
This study reported the establishment of a chemically defined culture system that supports tooth reconstitution and detailed how co-stimulation of specific signaling pathways can sustain tooth development stages and initiate enamel formation, providing insights into tooth regeneration mechanisms.
research Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity
This study found that Gelatinase A activity is linked to the absence of type VII collagen during human fetal skin development, indicating its role in remodeling the basement membrane zone.
research Formation of the cornified envelope
This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.
research Epidermal cyst of temporal bone as a delayed complication of myringoplasty
This study reports a rare case of an epidermal cyst localized in the temporal bone, potentially as a complication of myringoplasty, marking only the fifth such report in English-language literature.
research The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche
Nephronectin helps attach muscle cells to hair follicles.
research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species
This study found that CD90+ cells, resembling mesenchymal stem cells, are abundantly present in the lower part of anagen hair follicles in dogs.
research Vertebral epidermal transamidases
Transamidases are present in the epidermis but their exact role is unclear.
research Early-stage bilayer tissue-engineered skin substitute formed by adult skin progenitor cells produces an improved skin structure in vivo
This study concluded that early-stage tissue-engineered skin substitutes, developed using skin progenitor cells, had a better graft efficiency and supported hair follicle formation, which may improve wound healing outcomes.