Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study suggests that the anticonvulsant effects of deoxycorticosterone in young rats may be mediated by its metabolites and interactions with multiple receptors, including mineralocorticoid and progesterone receptors.

This study found that finasteride altered androgen receptor expression in the rat epididymis without affecting the morphology of epididymal epithelium, suggesting a change in hormonal status.

In this study, researchers observed that the epidermal specializations on the tail scales of Lygodactylus lizards, including sensory organs and specific secretory glands, are fully restored with similar structure and distribution on regenerated tails.

This document details the usage policy for full-text reproduction from Durham E-Theses, providing guidelines for personal, educational, and non-commercial purposes without altering the text.

In this study, treatment with DHEA induced mild to moderate hyperplasia of sebaceous glands in ovariectomized rats, which was prevented by the antiandrogen Flutamide but not by the antiestrogen EM-800.

This study provides genomic and epigenomic insights into the white wax scale insect, highlighting high methylation levels and differential hormone profiles linked to its sexual dimorphism and developmental differences.

Balanced protease activity is crucial for healthy skin and hair development.

This study identified a recurrent mutation in the endothelin receptor type A associated with mandibulofacial dysostosis with alopecia, and proposed a mechanism involving increased ligand affinity due to structural changes.

This study found that NNAT is localized in both undifferentiated and differentiated cells across various rat tissues and has cell-specific intracellular localization, suggesting distinct functional roles.

This case report observed that after 6 months of treatment with topical cetirizine and oral vitamin D, hair density and quality improved in three girls with congenital hypotrichosis due to ectodermal dysplasia.

This perspective highlights the potential of reptile integument as an experimental model to understand the evolution of amniote skin structures, but reports no new research findings.

This study found that the unique crest feather formation in Polish chickens is driven by a 195-bp duplication in the HoxC10 gene region, which alters gene expression by modifying the genomic structure, suggesting a mechanism for diverse integumentary appendages in birds.

This study found that Hex gene expression patterns in chick embryo dorsal skin during feather bud development suggest a significant role in initiating feather morphogenesis.

In this study, researchers found that Derinat, a TRPCs inhibitor, reduced oxidative stress and prolonged the anagen phase of hair growth in mice, supporting its potential as a therapy for androgenetic alopecia by improving clinical outcomes and enhancing quality of life for those affected.

In this study, treatment with finasteride altered the expression patterns of antioxidant enzymes in the epididymis of rats, potentially affecting its protective function for spermatozoa.

This report details the case of an 11-year-old girl with APECED syndrome carrying a unique homozygous mutation in the AIRE gene, the first of its kind documented.

This study found that after topical application in rats, 1,24-dihydroxyvitamin D3 absorbed through both the stratum corneum and hair follicles, with about 30% excreted via the faeces.

This study found that variations in Kv1 channel gene expression in the electric organ of Sternopygus correlate with sex differences and individual variations in their electric communication signals.

Terrestrial vertebrates have balanced keratin gene clusters, unlike teleost fish.

In this study, researchers developed "Akaro Spectra," an antiparasitic tablet for dogs using cryodestruction of plant materials, which showed 100% efficacy against Otodectes cynotis ticks by the second day and 93.76% efficacy against Ixodes, Dermacentor, and Rhipicephalus ticks.

This laboratory study found that dendrobium officinale polysaccharide (DOP) stimulated hair follicle and hair growth in mice by activating the WNT signaling pathway.

In this study, overexpression of ornithine decarboxylase accelerated basal cell carcinoma in Ptch1+/– mice under UVB exposure, while its inhibition reduced tumor induction, suggesting potential chemoprevention strategies in humans.

This study observed that activin A and its antagonist follistatin influence the differentiation of inner ear hair cells by regulating the expression of the transcription factor ATOH1.

This study found that the ID2 gene was highly expressed in bulge-derived keratinocytes when exposed to contact sensitizers and may serve as a marker to distinguish sensitizers from irritants during in vitro testing.

This study found that mitochondrial oxidative phosphorylation in epithelial cells is necessary for proper enamel formation and odontoblast differentiation in developing incisor teeth in K320E-Twinkle Epi mice.

The study found that exogenous decorin administration accelerated the anagen phase and delayed the catagen transition, suggesting it may act as a positive regulator of the hair cycle.

In this study, researchers found that dentin sialoprotein and phosphophoryn are present in rat and mouse hair follicles, suggesting these proteins may play a role in hair follicle development, similar to their role in dentin mineralization.

In this study, researchers successfully synthesized a rigid 3a-arylhexahydropentalene-1,6-dione from the easily accessible starting material cyclopent-2-en-1-one, highlighting a structural motif common in natural products and pharmaceuticals.