October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
September 2023 in “Cutis” This study presents a case of a 6-month-old infant girl with hypotrichosis and an alopecic plaque in the occipital region, characterized by broken and dystrophic hairs with follicular papules and perifollicular hyperkeratosis, suggesting a diagnostic consideration.
April 2023 in “JOJ dermatology & cosmetics” In this study, researchers highlighted the complexity of managing psychocutaneous disorders, emphasizing the need for a multidisciplinary approach involving dermatologists, psychiatrists, family physicians, and social support to address associated psychiatric diagnoses, risk factors like suicide, and ensure effective treatment.
February 2010 in “Journal of the American Academy of Dermatology” This case report describes a 4-month-old boy with anhidrotic ectodermal dysplasia and immunodeficiency who showed minimal improvement with initial treatments but significant improvement after an umbilical cord blood transplantation.
June 1997 in “Australasian Journal of Dermatology” This article discusses hair and nail research contributions in dermatology but reports no new clinical findings.
This review discusses the roles and characteristics of skin stem cells, their niches, and signaling pathways in skin maintenance, aging, and cancer, highlighting their potential in therapeutic applications but presenting no new clinical findings.
31 citations
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July 2017 in “Clinical Science” This review discusses the role of microRNAs in skin function and potential therapeutic applications, emphasizing their importance in wound healing and disease management, though it reports no new experimental findings.
16 citations
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January 2007 in “Dermatology” This review summarizes recent progress in human hair follicle bulge cell research, particularly the characterization and isolation of these stem cells, but reports no new experimental results.
5 citations
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November 2021 in “Skin appendage disorders” This review discusses the quality of life impact of hair loss disorders and potential psychological treatment approaches but reports no new clinical results.
5 citations
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January 2017 in “Clinics in Dermatology” This review discusses the challenges of diagnosing and managing somatization in dermatology patients, highlighting the need for comprehensive evaluation of unexplained dermatologic symptoms, and reports no new results.
3 citations
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May 2023 in “Current Molecular Medicine” This review discusses the distinction between platelet-rich plasma and stem cell-based therapies in regenerative medicine, highlighting their different roles and stressing the importance of honest representation by commercial and health entities.
November 2025 in “Frontiers in Immunology” This review integrates studies on mouse models and human clinical observations to highlight the role of immune cells in skin development and how their dysregulation leads to skin disorders, suggesting potential therapeutic pathways for skin regeneration.
January 2024 in “Medical Research Archives” This source highlights the emerging field of psychodermatology, which examines the interplay between psychological factors and skin disorders, noting a historical lack of attention due to inadequate professional training and emphasizing the need for integrated care involving dermatologists, psychiatrists, and psychologists.
November 2023 in “Frontiers in cell and developmental biology” This source reviews mechanisms and existing treatments for hair aging, highlighting factors like oxidative stress and DNA repair defects that affect hair follicle and stem cell function, and discusses research limitations and future directions in the field.
1 citations
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September 2015 in “Serbian Journal of Dermatology and Venereology/Serbian Journal of Dermatology and Venerology” This paper presents a case of a young male with a family history, showing overlap between ulerythema ophryogenes and keratosis follicularis spinulosa decalvans, affecting both eyebrows and scalp with cicatricial patchy alopecia.
90 citations
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June 2006 in “The American Journal of Dermatopathology” This review outlines the classification, histopathologic presentation, and pathogenetic concepts of scarring and nonscarring alopecias, reporting no new clinical results and emphasizing the need for clinicopathologic correlation.
86 citations
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December 2001 in “Experimental dermatology” This review classifies mutant mice with hair abnormalities into six categories, providing an annotated table that serves as a reference for understanding the molecular controls of hair growth.
74 citations
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October 2012 in “The American Journal of Human Genetics” This study found that loss-of-function mutations in the HOXC13 gene cause autosomal-recessive pure hair and nail ectodermal dysplasia, emphasizing its role in hair and nail development.
66 citations
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June 2010 in “Experimental Dermatology” This paper argues that the cycling hair follicle serves as a valuable model for systems biology research, highlighting its potential for translational medicine.
44 citations
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November 1998 in “Australasian Journal of Dermatology” This review provides a framework for diagnosing acquired scalp alopecias and discusses both non-scarring and scarring types, but reports no new clinical results.
43 citations
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February 2013 in “Developmental dynamics” This study found that Eda and activin A regulate Foxi3 expression, which may contribute to the development of hypohidrotic ectodermal dysplasia by affecting Foxi3 activity in ectodermal appendages like hair and teeth.
30 citations
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August 1983 in “Pediatric Clinics of North America” Most hair loss in children is caused by a few common conditions, and it's important to diagnose these properly and support the child's mental health.
22 citations
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November 2014 in “Psychiatric Clinics of North America” This article reviews stress-related skin reactions, psychodermatology, and neuropsychiatric skin manifestations, and reports no new clinical results.
11 citations
,
March 2001 in “Clinics in Dermatology” This article discusses the complexities in diagnosing hair shaft disorders and the potential insights hair microscopy can provide, without reporting new clinical findings.
7 citations
,
November 2000 in “Clinics in Dermatology” In this study, pediatric patients with overt polyautoimmunity frequently had systemic lupus erythematosus as an index disease, with clustering patterns revealing familial influence on autoimmune disease aggregation.
7 citations
,
April 2012 in “Biomolecular concepts” This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.
6 citations
,
February 2013 in “Veterinary Dermatology” This case report describes the first documented occurrence of pili torti in a healthy young adult cat, marked by noninflammatory and nonpruritic symmetrical multifocal alopecia.
4 citations
,
November 2017 in “Scientific Reports” This study compiled an archive of 684 genes associated with monogenic hair disorders, identifying previously unrecognized components of Hippo signaling and proposing a new biologically-grounded disease taxonomy.
4 citations
,
January 2014 in “International Journal of Trichology” This report presents a 12-year-old male with symptoms indicative of Marie-Unna type hereditary hypotrichosis, characterized by a specific pattern of hair loss evolving with age.
3 citations
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January 2016 in “Journal of cosmetology & trichology” This report suggests that correcting nutritional deficiencies may improve hair quality in patients with Monilethrix and similar hair shaft disorders, though it is not a cure.