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In this study, researchers observed that the sebaceous gland niche in mice allows for Wnt-induced hair follicle differentiation, unlike the non-permissive bulge.

This study found that applying a tocotrienol-rich phytochemical topically induced hair follicle development in adult mice, revealing a new epidermal pathway involving E-cadherin and β-catenin.

This study suggests that the AGA risk haplotype in Europeans was driven to high frequency by positive selection, likely associated with a variant in the EDA2R gene.

This study found that inducing Atoh1 expression in transgenic mice is sufficient to generate new Merkel cells in the epidermis, with variations by skin location, developmental age, and hair cycle stage.

This study reports that hair follicles can mobilize ectopic progenitors for regeneration to repair damage from ionizing radiation. Augmenting WNT signaling enhanced this regenerative process and prevented radiation- and chemotherapy-induced hair loss, highlighting a potential approach to manage alopecia during cancer treatment.

This study describes the otolaryngologic manifestations and multidisciplinary management strategies for 12 patients with ectodermal dysplasia, emphasizing the importance of early recognition for effective treatment.

This study found that keratin immunohistochemistry suggests neoplastic cells in eccrine and apocrine poromas are closely related to dermal sweat duct cells, but cannot differentiate these poromas based solely on keratin patterns.

In this study, researchers found that eccrine sweat glands in human scalp skin are morphologically integrated into the pilosebaceous unit, suggesting they form a common homeostatic tissue environment with adjacent structures.

In this study, researchers found no hypertrophy in axillary sweat glands of hyperhidrotic patients, with eccrine gland clear cells being the primary site of fluid transport and no evidence of apoeccrine glands.

The study reported a significant genotype–phenotype correlation in prepubescent males with XLHED, particularly in the severity of skin and hair manifestations between those with different EDA mutations.

This study found that Ecklonia cava enzymatic extract, particularly its component dieckol, promoted hair growth by increasing dermal papilla cell proliferation and inhibiting 5α-reductase activity in cultured vibrissa follicles and C57BL/6 mice.

This study found that human sweat glands contain unique stem cells with significant multilineage differentiation potential and self-renewal abilities, suggesting promising clinical applications due to easy biopsy access.

This research identified K31 as a new marker for distinguishing clear secretory cells in human eccrine sweat glands, aiding in differentiating between distinct cell types within these glands.

This study found that individuals with ectodermal dysplasias often have a reduced secretion rate of submandibular saliva and altered protein concentrations, suggesting routine salivary tests may be beneficial in this population.

This study investigated the histopathology of ectodermal dysplasia/skin fragility syndrome, identifying specific skin and hair abnormalities associated with PKP1 gene mutations in two young female patients.

This review discusses recent advances in understanding the Eda pathway's role in developmental biology, and highlights ongoing trials and areas for further research, including Eda's potential involvement in cell processes and disease.

This study reports that eccrine sweat glands in mice predominantly develop on the footpads, offering a reference for skin research involving genetically engineered mice.

This study found that a novel ECM patch combining human fibroblast-derived matrix and PVA hydrogel, seeded with human mesenchymal stem cells, significantly improved wound healing and tissue regeneration in a mouse model.

In this study, researchers identified a novel congenital skin disorder in Chesapeake Bay retrievers, linked to a plakophilin-1 deficiency due to a genetic mutation, marking the first known occurrence in an animal species.

Stem cells in eccrine glands could be used for regenerative medicine.

This study found that the HoxC gene cluster plays a critical role in the development of ectodermal organs, including hair and nails, with mammalian-specific enhancers increasing transcription levels during development.

In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.

This study found that AIRE, a usually nuclear protein, is expressed in the cytoplasm of human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17, potentially impacting ectodermal abnormalities in APECED syndrome.

In this study, finasteride was found to reduce costs associated with benign prostatic hyperplasia compared to watchful waiting and terazosin, especially in men with higher prostate-specific antigen levels.

This review discusses recent advances in developmental tissue engineering for regenerating ectodermal appendages like teeth and glands, emphasizing biomaterial selection and cell culture strategies, but reports no new experimental results.

This study found that disrupting Sox21 in developing teeth leads to severe enamel hypoplasia, regional osteoporosis, and abnormal hair formation, with impaired dental epithelial differentiation and regulation of hair follicle cell fate.

This study suggests that Ecklonia cava, particularly its component dioxinodehydroeckol, may promote hair growth by enhancing dermal papilla and outer root sheath cell activity in culture and mice models.

This review compiles information on traditional uses, phytoconstituents, and biological activities of Eclipta prostrata but reports no new experimental results; the authors call for more studies to understand its pharmacological mechanisms.

This case report describes a patient with Clouston's syndrome and alopecia who responded positively to topical treatment with minoxidil and tretinoin.

This case report describes a 16-year-old with ectrodactyly-ED-clefting syndrome, where scarring alopecia with follicular involvement appeared during puberty, possibly due to anatomic hair abnormalities.