Salivary Gland Function in Persons with Ectodermal Dysplasias

    September 2003 in “ European journal of oral sciences ”
    Hilde Nordgarden, Kari Storhaug, Ståle Petter Lyngstadaas, Janicke Liaaen Jensen
    TLDR People with ectodermal dysplasias often have reduced saliva production and should get saliva tests.
    The study aimed to understand salivary gland involvement in ectodermal dysplasias (EDs) by comparing 39 individuals with ED (median age 12 years; 24 males, 15 females) to a healthy control group. It was found that 33% of the ED group had significantly reduced secretion of submandibular and/or parotid saliva, along with low unstimulated and/or chewing-stimulated whole salivary flow. The median secretory rate of submandibular saliva was reduced in the ED group, while the median concentrations of some protein parameters were increased, though the overall protein output was normal or reduced. Submandibular glands were more affected than parotid glands in EDs. The study concluded that salivary secretory tests are recommended for individuals with known or suspected EDs.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    2 / 2 results

      community OFFICIAL Multi-Center Verteporfin Trial Recruitment

      in Research/Science  248 upvotes 3 weeks ago
      Recruitment for a verteporfin trial and a separate hair cloning trial using verteporfin and other methods is underway, with locations in Jordan, NYC, Beverly Hills, and Memphis. Dr. Bloxham is conducting the hair cloning trial, and interested participants are encouraged to contact him directly.

      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

    Similar Research

    5 / 1000+ results