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PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Muscles and nerves that cause goosebumps also help control hair growth.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Targeting the skin's endocannabinoid system could help treat skin disorders.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.