research Gonadal Sex Steroids: Production, Action, and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
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research Clinical and Phototrichogrammatic Evaluation of Estradiol Replacement Therapy on Hair Growth in Postmenopausal Japanese Women with Female Pattern Hair Loss: A Pilot Study
Hormone replacement therapy may improve hair growth in the frontal hairline of postmenopausal women with hair loss.
research Cardiovascular Risk in Women with Premature Ovarian Insufficiency Compared to Premenopausal Women at Middle Age
Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.
research Occult Ovarian Leydig Cell Tumor: When Laboratory Tells More Than Imaging
Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.
research Hirsutism: Evaluation and Treatment
Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
research Clinical and Metabolic Implications of Obesity in Prostate Cancer: Is Testosterone a Missing Link?
Higher BMI and lower testosterone are linked to more aggressive prostate cancer.
research Exploring the Efficacy of Testosterone Undecanoate in Male Children with 5α-Reductase Deficiency
Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.
research Physiology of Testicular Function
The testes produce sperm and hormones essential for male development.
research Managing Hair Loss in Midlife Women
Effective treatment for midlife women's hair loss is limited, with 5% minoxidil foam being the only proven option for the most common type.
research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility
COVID-19 may harm male fertility and damage the reproductive system.
research A Case Report of the Association Between Canine Hypothyroidism and Diabetes
This case report highlights the association between canine hypothyroidism and diabetes mellitus through the example of an 11-year-old male Lhasa Apso exhibiting symptoms like apathy, anorexia, bilateral symmetric alopecia, polyuria, polydipsia, and cataracts. Blood tests confirmed the presence of both hypothyroidism and diabetes mellitus. Hypothyroidism, the most common endocrine disorder in dogs, can lead to polyendocrine syndromes, including diabetes, due to immune-mediated attacks on endocrine system antigens. The report underscores the importance for veterinarians to recognize clinical signs and conduct thorough testing for effective diagnosis and treatment of these conditions.
research Southern African HIV Clinicians Society Gender-Affirming Healthcare Guideline for South Africa
The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.
research Human Hair as a Testing Substrate in the Era of Precision Medicine: Potential Role of Omics-Based Approaches
Human hair shows promise for non-invasive medical testing, but more research is needed to standardize its use.
research Toxoplasma Gondii Infection and Testosterone Alteration: A Systematic Review and Meta-Analyses
Toxoplasma gondii infection may increase testosterone levels in males.
research Postmenopausal Virilization After Spousal Use of Topical Androgens
A woman developed male traits from accidental contact with her husband's testosterone gel.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Relationship Between Serum Anti-Müllerian Hormone and Intrafollicular AMH Levels in PCOS Women
Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.
research Red Ginseng Monograph
Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.
research COVID-19 Pandemic: What About the Gonads?
COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.
research Benefits of Testosterone Replacement and Methods of Substitution
Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
research The Effects of Transdermal Dihydrotestosterone in the Aging Male: A Prospective, Randomized, Double-Blind Study
Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
research Clinical Characteristics of Polycystic Ovary Syndrome: Investigating Differences in White and South Asian Women
South Asian women with PCOS present with different symptoms compared to White women, influenced by ethnicity, obesity, and age.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS)
The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
research Severe Cutaneous Adverse Reactions to Drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research Endocrinology Overview: Male Reproductive Endocrinology and HPT Axis
The document explains how male reproductive hormones work and affect the body.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Revisiting Hyper- and Hypo-Androgenism by Tandem Mass Spectrometry
The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
research Recommendations for Endocrine Treatment of Patients with Gender Dysphoria
The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.
research Ischemic Vaso-Occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report
Early treatment of pediatric lupus-related eye issues is crucial to prevent vision loss.