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Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

The consensus document recommends a comprehensive treatment plan for Hidradenitis Suppurativa, including various medications, surgery, lifestyle changes, and the need for more research and resources.

Severe COVID-19 may cause hair loss, and doctors recommend supplements and topical treatments to manage it.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Familial frontal fibrosing alopecia affects premenopausal women too, and early diagnosis is important, but no proven medication exists yet.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

FPHL common in Taiwanese women; risk factors include BMI, high glucose, early puberty, fewer childbirths, oral contraceptives, and UV exposure.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

People with psoriasis are more likely to have Metabolic Syndrome than those without psoriasis.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Patients with chronic skin conditions on systemic treatments did not have worse COVID-19 outcomes and could resume their treatments after recovery.