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This study identified orally available itaconate derivatives that improve cellular permeability and bioavailability, with specific POC-based prodrugs showing significant inhibition of inflammatory cytokines in human epidermal keratinocytes and favorable oral pharmacokinetics, highlighting their potential for treating systemic and skin disorders.

This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.

This study found that tofacitinib may be effective for treating pediatric rheumatic diseases, with especially promising results in patients with autoinflammatory diseases, arthritis and alopecia, and juvenile dermatomyositis.

This review of Tridax procumbens highlights its pharmacological and phytochemical potential, noting the presence of biologically active compounds and suggesting its value as a basis for developing new plant-based therapeutics due to its diverse medicinal properties and low toxicity.

This review discusses the properties and applications of doxycycline in dermatology and reports no new clinical results, emphasizing its potential for treating various dermatological conditions.

This study found that Dex-loaded hyaluronic acid hydrogel microneedles significantly reduced pain in an acute inflammatory visceral pain model without sedation, suggesting a promising and patient-friendly alternative to intravenous delivery.

This review discusses the traditional uses of Tridax procumbens for wound healing, antifungal, and antibacterial purposes, but reports no clinical findings.

This research highlights that while JAK inhibitors are effective for various inflammatory conditions, studies raise concerns about increased risks of venous and arterial thromboembolism, and cancer, particularly with tofacitinib and baricitinib, leading to European guidelines recommending caution in high-risk patients.

In this study, researchers evaluated the antifungal effectiveness of topical products on infected kitten hair, finding most were effective after one application, with enilconazole and lime sulfur showing residual activity; however, 0.15% ketoconazole with chlorhexidine had no such lasting effect.

This study found that dutasteride-loaded nanostructured lipid carriers coated with a stearic acid-chitosan oligomer are stable, less cytotoxic, and suitable for topical delivery to promote hair growth.

This study found that Diane®, a combination of cyproterone acetate and ethinyl estradiol, is an effective contraceptive and treatment for acne and seborrhea, but less effective for pronounced hair growth.

The committee unanimously voted against recommending approval of the injectable cisplatin/epinephrine gel IntraDose for certain head and neck cancer patients, citing insufficient clinical benefit and concerns about toxicity in this study.

Tofacitinib helped a 19-year-old regrow hair after other treatments failed.

This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.

This article discusses the chronic inflammatory skin diseases acne keloidalis nuchae and dissecting cellulitis of the scalp, focusing on their shared etiology and differing progression, and reports no new clinical findings.

Tofacitinib helped regrow hair in a patient with severe hair loss and improved their quality of life without side effects.

In this study, Typhonium flagelliforme leaf-ethanolic extract combined with natural interferon was observed to stabilize body weight, inhibit tumor growth, and reduce mitosis, angiogenesis, and certain protein expressions in carcinogen-induced tumors in female mice, suggesting potential antitumor effects.

In this case report, tofacitinib was initiated in a 20-year-old female with alopecia universalis resistant to topical treatments, but resulted in a mild peripheral neuropathy side effect.

In this study, cyclic ADP-ribose (cADPR) treatment in human hair follicle dermal papilla cells was associated with increased intracellular calcium retention and activated anagen-related signaling without causing significant cytotoxicity, indicating its potential impact on hair growth processes.

In this study, the researchers observed that the severity of capecitabine-induced hand-foot syndrome in advanced gastric cancer patients was not linked to the IVS14+1G→A mutation in the DPYD gene.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

This study demonstrated that in live rodents, actin filaments adjust their structure to facilitate membrane transfer between cellular compartments with different biophysical properties.

In this case report, an 11-year-old girl with dissecting cellulitis of the scalp showed an excellent response to oral isotretinoin after other treatments failed, highlighting the treatment challenges and need for awareness in managing this rare condition.

This review discusses the use of tofacitinib as a treatment for plaque psoriasis, highlighting its efficacy and safety in clinical trials, but notes unresolved questions regarding long-term safety.