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The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Lowering testosterone speeds up wound healing in male mice.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

DHT may increase the risk of heart disease and death in elderly men.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

BMP2 and BMP7 have opposite roles in feather formation.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.