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The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.

Finasteride-loaded nanogels are effective, safe, and improve drug absorption through the skin.

Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.

Baricitinib may effectively treat nail changes in alopecia areata.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.

Minoxidil is less effective on eyebrows and eyelashes than scalp hair because these areas have lower enzyme activity needed to activate the drug.

Finasteride may help some women with hair loss, but better options exist.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Oral minoxidil effectively reduces hair shedding in women with CTE, with no major side effects.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Using microneedles before applying eflornithine cream can make it more effective at stopping hair growth.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Laser and light therapies, especially the 308 nm excimer laser, are effective and safe for treating alopecia areata, but more research is needed.

Rivaroxaban can cause liver injury, allergic reactions, blood vessel inflammation, and hair loss, but these side effects are rare.

Inflammation around hair follicles leads to hair loss, and treatments should focus on reducing this inflammation and other factors for effectiveness.

Microneedling is effective for skin rejuvenation and various skin issues, but more research is needed to confirm its safety and effectiveness.

Fractional lasers could help hair regrowth in androgenic alopecia, but more research is needed to confirm their effectiveness and safety.

Skin needling is a safe, effective, and affordable treatment for various skin issues and enhances other aesthetic procedures.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.