research Finasteride-Induced Gynecomastia
Finasteride can cause enlarged breasts.
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research Human-Derived Immortalized Dermal Papilla Cells With Constant Expression of Androgen Receptor
Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
research In Vivo Evaluation of the Efficacy, Toxicity, and Biodistribution of PLGA-DMSA Nanoparticles Loaded with Itraconazole for Treatment of Paracoccidioidomycosis
Itraconazole-loaded nanoparticles are more effective and less toxic for treating fungal infections than conventional oral itraconazole.
research Non-Hormonal Treatment Options for Regulation of Menstrual Cycle in Adolescents with PCOS
Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.
research Hair Loss Associated With Escitalopram: Do SSRIs Affect Melatonin at the Hair Follicle?
The antidepressant escitalopram likely caused hair loss in a patient.
research News in Brief
Breast cancer survivors may have a higher risk of falls, tamoxifen could prevent breast cancer and deaths, new guidelines urge caution with prostate cancer therapy, and early balding in men may indicate a higher prostate cancer risk.
research Finasteride
Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.
research C19 and C21 5β/5α Metabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
research Identification of Sirtuin 1 as a Promising Therapeutic Target for Hypertrophic Scars
Sirtuin 1 could be a potential drug target for treating hypertrophic scars.
research Bone Density Is Normal in Male Rats Treated with Finasteride
Finasteride doesn't affect bone density in male rats.
research Organic and Biogenic Nanocarriers as Bio-Friendly Systems for Bioactive Compounds Delivery: State-of-the-Art and Challenges
Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.
research 4-Octyl Itaconate Alleviates Cisplatin-Induced Ferroptosis Possibly Via Activating the NRF2/HO-1 Signalling Pathway
4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.
research Repurposing of Linagliptin and Similar FDA Approved Drugs as Antidiabetic Agents
Pranlukast and mirabegron may work as new diabetes drugs.
research Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase
Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
research Treatment With and Withdrawal From Finasteride Alter Ethanol Intake Patterns in Male C57BL/6J Mice: Potential Role of Endogenous Neurosteroids
Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.
research Finasteride Attenuates Pathological Gambling in Patients With Parkinson's Disease
Finasteride reduces gambling symptoms in Parkinson's patients.
research Finasteride-Associated Male Infertility
Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.
research Minoxidil-Induced Stevens-Johnson Syndrome
Minoxidil can cause severe skin reactions like Stevens-Johnson syndrome in rare cases.
research Alopecias Due to Drugs and Other Skin and Systemic Disorders
Hair loss can be caused by stress, infections, drugs, and various diseases, with treatment depending on accurate diagnosis.
research Polycystic Ovary Syndrome and Oxidative Stress: From Bench to Bedside
Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.
research An Antifungal for Antidiuresis? Fluconazole's Potential in Treating Nephrogenic Diabetes Insipidus
Fluconazole might be a new treatment for a type of diabetes that affects water balance in the body.
research Brown Adipose Tissue as an Innovative Approach for Polycystic Ovary Syndrome Treatment: A Narrative Review
More research is needed before using brown fat to treat polycystic ovary syndrome.
research The Potential Involvement of Cholinergic System in Finasteride Induced Cognitive Dysfunction
Finasteride might affect memory by impacting cholinergic system.
research The Pharmacology of Methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research Rethinking Biotin Therapy for Hair, Nail, and Skin Disorders
Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.
research Pharmacology and Pharmacokinetics of Minoxidil
Minoxidil treats high blood pressure and side effects can be managed.
research Finasteride Treatment Inhibits Adult Hippocampal Neurogenesis in Male Mice
Finasteride reduces new brain cells in male mice, possibly causing depression.
research Plasma C19 Steroid Sulfate Levels and Indices of Androgen Bioavailability in Female Pattern Androgenic Alopecia
Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.