research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
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research Follow-Up of Adverse Drug Reactions from Peginterferon Alfa-2b—Ribavirin Therapy
Peginterferon alfa-2b and ribavirin therapy for hepatitis C can cause serious side effects, some different from those reported in clinical trials.
research Androgenetic Alopecia: Drug Safety and Therapeutic Strategies
Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Association Between Gender and Drug Cost for Over-the-Counter Minoxidil
Women pay more for the same 5% minoxidil foam than men, but prices for liquid solutions are similar.
research Suspected Cutaneous Drug Toxicity in Rheumatoid Arthritis—An Evaluation
Most skin rashes in rheumatoid arthritis patients were not caused by their medication, and careful evaluation allowed most to keep taking their beneficial treatment.
research Novel Causes of Drug-Induced Occupational Asthma
Four new substances—minoxidil, ferrimanitol ovalbumin, clarithromycin, and glucosamine-hydrochloride—can cause occupational asthma.
research A Microscopy-Based Small Molecule Screen in Primary Neurons Reveals Neuroprotective Properties of the FDA-Approved Anti-Viral Drug Elvitegravir
The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
research Entrepreneurship in Off-Label Drug Prescription: Just What the Doctor Ordered!
The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.
research Ixekizumab Improves Physical Function, Quality of Life, and Work Productivity in Biologic Disease-Modifying Antirheumatic Drug-Naive Patients with Active Psoriatic Arthritis
Ixekizumab helps improve life quality, physical ability, and work performance in patients with psoriatic arthritis who haven't used biologic drugs before.
research Chemotherapy and Cutaneous Drug Reactions
Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.
research Molecular Insights Into the Formation of Drug-Polymer Inclusion Complex
The research shows how certain drugs can form stable structures with polymers, which is important for making new pharmaceuticals.
research Understanding the Formation Mechanism of Drug-Polymer Inclusion Complex by Structure Elucidation and Theoretical Calculation
The research shows how certain drug molecules form stable structures with polymers, which could help create new drug forms.
research Hepatotoxicity Secondary to a Weight Loss Drug, Orlistat: Consideration as a Differential Diagnosis
The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.
research Letter to the Editor: Androgenetic Alopecia; Drug Safety and Therapeutic Strategies
Dutasteride is a safe and effective treatment for hair loss.
research Spironolactone: An Anti-Androgenic and Anti-Hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
Spironolactone might help protect against severe lung problems in COVID-19 patients.
research Finasteride Inhibits the Progesterone-Induced Spike-Wave Discharges in a Genetic Model of Absence Epilepsy
Finasteride blocks progesterone's effect on absence seizures in rats.
research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Evaluation of the Efficacy of Transdermal Drug Delivery of Calcipotriol Plus Betamethasone Versus Tacrolimus in the Treatment of Vitiligo
Calcipotriol plus betamethasone with microneedling works better than tacrolimus for treating vitiligo.
research Compilation of a Comprehensive Gene Panel for Systematic Assessment of Genes That Govern an Individual’s Drug Responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research The Post-Finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption
Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
research A Prospective Observational Study on Drug Safety Monitoring and Pharmacoeconomics in Patients with Locally Advanced Unresectable NSCLC in a Tertiary Care Hospital
Carboplatin-paclitaxel is preferred for advanced lung cancer due to its balance of affordability and patient well-being.
research Albendazole Treatment of Echinococcosis in Humans: Effects on Microsomal Metabolism and Drug Tolerance
Albendazole treatment for echinococcosis can cause serious side effects and requires close monitoring.
research Synthesis and Characterization of Inclusion Complex of the Vasodilator Drug Minoxidil with β-Cyclodextrin
Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.
research Formulation of Sodium Valproate Nanospanlastics as a Promising Approach for Drug Repurposing in the Treatment of Androgenic Alopecia
Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.
research Intestinal Permeability Study of Minoxidil: Assessment of Minoxidil as a High Permeability Reference Drug for Biopharmaceutics Classification
Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.
research Evolution of Ritlecitinib Population Pharmacokinetic Models During Clinical Drug Development
Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.
research Isotretinoin for the Treatment of Facial Lichen Planopilaris: A New Indication for an Old Drug, a Case Series Study
Isotretinoin was not effective in treating facial lichen planopilaris.
research Changes in Growth and Distribution of Hair Associated with Psychotropic Drug Use
Psychotropic drugs can cause hair loss or excessive hair growth.