33 citations
,
September 2012 in “Wound Repair and Regeneration” This study found that the application of calreticulin significantly improved wound healing time and quality in diabetic mice, suggesting it may be an effective topical treatment for chronic wounds.
32 citations
,
January 2012 in “International Journal of Dermatology” This study reported that the most common skin side effect of epidermal growth factor receptor inhibitors was a papulopustular rash, treatable with symptom-targeted therapies, while drug suspension was rarely needed.
32 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Using minoxidil on balding men's scalps can increase hair growth, according to a 12-month study.
28 citations
,
July 2013 in “Journal of Craniofacial Surgery” In this study, hair follicle transplantation on scars showed varied success rates, with burn scars achieving better results than incision scars, and often requiring multiple procedures for optimal outcomes.
26 citations
,
August 2016 in “ACS Applied Materials & Interfaces” In this study, cell membrane remodeling with a thermoresponsive boronic acid copolymer was shown to rapidly form spheroids from cancer or cardiac cell lines under standard conditions, promising advances in tissue engineering.
24 citations
,
October 2016 in “Oncotarget” This study found that finasteride was associated with more reproductive adverse effects, including sexual dysfunction in men and fetal harm in women, compared to minoxidil in reported alopecia cases.
22 citations
,
October 2019 in “Cerebral cortex” This study found that testosterone and dihydrotestosterone are crucial for synaptic transmission and spine density in male hippocampal neurons, suggesting sex-specific effects of neurosteroids on brain development.
22 citations
,
January 2017 in “Advanced Healthcare Materials” This study found that thermoresponsive hydrogels can maintain mechanical memory in fibroblasts, enhancing wound healing compared to traditional trypsinized methods.
22 citations
,
February 2013 in “Wound Repair and Regeneration” In this study, CD109 overexpression in transgenic mice led to reduced inflammation and improved collagen organization during wound healing without affecting wound closure.
22 citations
,
August 2011 in “Journal of Supercritical Fluids” In this study, fraction No. 3 of Oryza sativa bran extract demonstrated high unsaturated fatty acid content and significant 5α-reductase inhibition, suggesting potential for developing anti-androgenic alopecia products.
21 citations
,
January 2006 in “Pediatrics” This review discusses how certain genetic, infectious, and metabolic conditions might influence disease severity and highlights the potential for new therapies, but it presents no new research findings.
21 citations
,
October 1978 in “The Journal of Clinical Pharmacology”
19 citations
,
November 2017 in “Journal of Pharmaceutical Sciences” This research investigated aqueous alginate-based hydrogels for delivering minoxidil and reported that using hydroxypropyl-β-cyclodextrin (HP-β-CD) with molar substitution 0.65 significantly enhanced minoxidil's solubility and skin permeability without damaging the epidermis, suggesting potential as an alternative to commercial minoxidil solutions.
19 citations
,
November 2012 in “British Journal of Dermatology” This study found that dopamine directly induces the catagen phase in human scalp hair follicles in vitro.
19 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that hair follicle germinative epidermal cells can form complex structures when associating with papilla cells in culture, unlike other types of epidermal cells.
18 citations
,
December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” The authors concluded that increased expression of the HSD11B1 gene in adipose tissue correlates with obesity markers and predicts insulin resistance, but this association is independent of polycystic ovary syndrome when adiposity is controlled for.
17 citations
,
January 2019 in “Journal of cancer” This study found that the medicinal formula YH0618 may reduce toxicity from the chemotherapy drug doxorubicin, improving side effects like hair loss and organ damage, while maintaining its anti-cancer effects.
17 citations
,
January 2016 in “American Journal of Epidemiology” This study suggests that any baldness, particularly moderate balding, is associated with a higher risk of fatal prostate cancer in men, supporting a possible link between hair loss and prostate cancer mechanisms.
16 citations
,
July 2020 in “Advanced functional materials” This review discusses the development and application of cell-derived matrices in regenerative medicine and disease modeling, presenting various fabrication techniques and future perspectives, but reports no new results.
15 citations
,
June 2020 in “Experimental Dermatology” This review discusses recent genetic findings on hormonal signaling pathways in androgenetic alopecia, reporting no new study results but highlighting the need for further investigation.
15 citations
,
September 2018 in “Dermatologic therapy” In this study, the use of two emollients significantly reduced itching severity in individuals with xerotic eczema, starting 30 minutes post-application, and improved skin moisture and lipid content over 14 days, while demonstrating good tolerance with few adverse events.
15 citations
,
June 2015 in “Human Cell” This study found that forming spheroids using silicone micro-wells improved the viability and neural differentiation potential of human adipose-derived stem cells after thawing.
15 citations
,
May 1997 in “Annals of Internal Medicine” This case report describes a patient with breast cancer who developed female androgenetic alopecia after starting tamoxifen therapy.
15 citations
,
January 1987 in “Electrophoresis” This study found that electrophoretic keratin typing of head hair can identify specific polypeptide patterns, suggesting potential applications in genetic and forensic investigations.
13 citations
,
September 2020 in “Dermatologic Therapy” This review discusses the use of microneedling for androgenetic alopecia and finds it promising for enhancing hair density and thickness, especially when combined with other treatments, but notes no standardized protocol exists yet.
12 citations
,
December 2002 in “Archives of Dermatology” This case report describes a 49-year-old woman with Sweet syndrome who experienced complete resolution of skin lesions after a prednisone treatment regimen.
12 citations
,
January 1978 The study observed that Friesian heifers experienced significant adaptation challenges to Kenya's equatorial conditions, taking around 18 months for their coat composition to resemble that of Dutch heifers in summer.
11 citations
,
April 2021 in “Advanced synthesis & catalysis” This study reports that the dye peri-xanthenoxanthene (PXX) can act as an efficient photocatalyst for various radical reactions, including complex dual catalytic processes and the synthesis of an investigational drug intermediate.
10 citations
,
July 2023 in “The Neuroscience Journal of Shefaye Khatam” In this review, the authors summarized the neuroprotective role of water- and fat-soluble vitamins in neurodegenerative diseases, highlighting their potential preventive and therapeutic effects through antioxidant and anti-inflammatory properties while acknowledging some studies question their preventive influence.
10 citations
,
April 2016 in “Research and reports in transdermal drug delivery” This review discusses the potential of follicular drug delivery systems to target the pilosebaceous unit and reports no new research findings.