research Minoxidil Therapy in Refractory Hypertension: Analysis of 155 Patients
Minoxidil lowers blood pressure effectively but may cause side effects.
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research Hair Repigmentation Associated with the Use of Lenalidomide: Graying May Not Be an Irreversible Process
An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.
research Targeting Neurosteroid Synthesis as a Therapy for Schizophrenia-Related Alterations Induced by Early Psychosocial Stress
A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
research Artepillin C and Other Herbal PAK1-Blockers: Effects on Hair Cell Proliferation and Related PAK1-Dependent Biological Function in Cell Culture
Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.
research Electron Paramagnetic Resonance Spectroscopy for Investigating Murine Telogen Skin After Spontaneous or Depilation-Induced Hair Growth
EPR spectroscopy showed that spontaneous hair growth results in thicker skin and less pigmented hair than depilation-induced growth.
research Where Have the Periods Gone? The Evaluation and Management of Functional Hypothalamic Amenorrhea
The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.
research Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster
Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
research Alopecia Areata in a Rhesus Monkey (Macaca Mulatta)
The monkey's hair loss was due to an autoimmune disease, not genetics.
research Update in Minimally Invasive Periorbital Rejuvenation with a Focus on Platelet-Rich Plasma: A Narrative Review
PRP is effective for improving the appearance around the eyes.
research Steroid 5α-Reductase 2 Deficiency Leads to Reduced Dominance-Related and Impulse-Control Behaviors
Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
research Clinical Repigmentation Patterns in Pediatric Vitiligo
The study found that the most common repigmentation pattern in children with vitiligo is a combination of patterns, with a new medium spotted pattern identified.
research HGF/SF Increases Number of Skin Melanocytes but Does Not Alter Quality or Quantity of Follicular Melanogenesis
HGF/SF increases skin melanocytes but doesn't change melanin type or amount.
research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research Finasteride Inhibited Brain Dopaminergic System and Open-Field Behaviors in Adolescent Male Rats
Finasteride affects young male rats' brain function and behavior negatively.
research Finasteride Inhibits Melanogenesis Through Regulation of the Adenylate Cyclase in Melanocytes and Melanoma Cells
Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth
Low ERCC3 gene activity is linked to non-pigmented hair growth.
research Functionally Distinct Melanocyte Populations Revealed by Reconstitution of Hair Follicles in Mice
Only skin melanocytes, not other types, can color hair in mice.
research Treatment of Androgen Excess in Females: Yesterday, Today, and Tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research A Machine Learning and Network Framework to Discover New Indications for Small Molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Heterogeneity of Neural Crest-Derived Melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
research Elicitor Mediated Enhancement of Wedelolactone in Cell Suspension Culture of Eclipta Alba (L.) Hassk
Adding yeast extract and methyl jasmonate to Eclipta alba cell cultures increased the production of the compound wedelolactone.
research Psychosocial Aspects of Hair Loss
Hair loss can cause serious mental health problems and treating it requires a team of experts.
research Phenolic Composition, Enzyme Inhibitory, and Antioxidant Activity of Bituminaria Bituminosa
The water extract of Bituminaria bituminosa, high in phenolic compounds, shows strong antioxidant and enzyme inhibitory potential.
research The Scientific Legacy of Stephen Rothman
Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.
research Structure and Function of the Skin
The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
research New Developments in Stem Cell Biology and Therapy: Meeting Report from the Working Group of the German Society for Hematology and Oncology
The meeting highlighted important advances in stem cell research and its potential for creating new medical treatments.
research Effects of Non-Contingent Cocaine on 3alpha-Androstanediol: Disruption of Male Sexual Behavior
Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
research Stem Cells of the Hair Follicular Tissue: Application in Cell-Based Therapy for Vitiligo
Hair follicle stem cells could be used to treat the skin condition vitiligo.
research Cutaneous Drug Eruptions Associated with the Use of Biologics and Cutaneous Drug Eruptions Mimicking Specific Skin Diseases
Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.
research Dermal Papilla Regulation of Hair Growth and Pigmentation
Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.