Clinical Repigmentation Patterns in Pediatric Vitiligo

    April 2016 in “ British Journal of Dermatology ”
    Emily Yiping Gan, Thibaut Gahat, Muriel Cario‐André, Julien Sénéschal, Khaled Ezzedine, Alain Taı̈eb
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    TLDR The study found that the most common repigmentation pattern in children with vitiligo is a combination of patterns, with a new medium spotted pattern identified.
    The study analyzed repigmentation patterns in 109 pediatric vitiligo patients, examining 172 lesions. It found that the combined repigmentation pattern was most prevalent (62%), followed by diffuse (25%), marginal (6%), perifollicular (5%), and the newly identified medium spotted repigmentation (2%). The combined pattern was more common in segmental vitiligo, while the diffuse pattern was more frequent in non-segmental vitiligo. The medium spotted pattern, characterized by circular macules wider than 5mm, was associated with areas of low hair follicle density. The study, limited by its retrospective design and small subgroup sizes, suggests that pediatric vitiligo repigmentation patterns may differ from adults and that the medium spotted pattern warrants further investigation. Repigmentation did not significantly vary with skin color, and the diffuse pattern was notably more common on the eyelids. Further research with larger cohorts is needed to better understand these patterns, especially the medium spotted repigmentation.
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