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Glossary Segmental Vitiligo

localized skin depigmentation affecting one body segment

Segmental Vitiligo is a type of vitiligo characterized by the loss of skin color in patches, typically affecting only one side or segment of the body. Unlike the more common generalized vitiligo, segmental vitiligo often appears at a younger age and progresses for a few years before stabilizing. It is believed to be associated with the nervous system, and the depigmented patches usually follow a dermatomal distribution, which is the area of skin supplied by a single spinal nerve.

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research A case of simultaneously occurring lichen sclerosus and segmental vitiligo: connecting the underlying autoimmune pathogenesis

22 citations , September 2008 in “International Journal of Dermatology”

This case report describes a 41-year-old woman with segmental vitiligo and lichen sclerosus in the perineal region, where treatment with clobetasol ointment improved repigmentation and resolved many symptoms, although some scaling persisted.

research Segmental Vitiligo and Hair Curling After Interferon α and Ribavirin Treatment for Hepatitis C

14 citations , January 2006 in “Skinmed”

A woman developed white patches on her skin and curly hair after hepatitis C treatment, likely due to the medication interferon alpha.

research Preservation of melanoblasts of white hair follicles of segmental vitiligo lesions: A preliminary study

7 citations , May 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

This preliminary study observed that melanoblasts are preserved in the white hair follicles of segmental vitiligo lesions.

research Segmental Vitiligo

2 citations , January 2019 in “Springer eBooks”

This review discusses segmental vitiligo as part of the vitiligo clinical spectrum and highlights its role as a model for studying repigmentation, but reports no new clinical results.

research Neurological Mechanisms Exploration and Therapeutic Targets in Segmental Vitiligo Accompanied by White Hair

1 citations , April 2025 in “Pigment Cell & Melanoma Research”

This article reviews the underlying mechanisms of segmental vitiligo with white hair, focusing on skin and hair follicle melanocytes, and proposes potential targets for treatment, highlighting neuroendocrine factors as possible contributors to the condition.

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community One full year of treatment before and after

in Progress Pictures 18 upvotes 2 years ago

A user shared their one-year progress with hair loss treatment, using topical minoxidil, 2% keto shampoo, microneedling, and finasteride. They plan to start dutasteride and are considering switching to oral minoxidil.

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Clinics

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SMP
Madhulika Upadhyay – Permanent Makeup & Vitiligo Camouflage ClinicNew Delhi, Delhi · IN

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