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The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.

Hair follicles repair 3D injuries using a 2D healing process.

Cell aging can be both good and bad for tissue repair.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.

CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.

Photobiomodulation helps reduce pain, lessen inflammation, heal wounds, and can be used in skin treatments. It also boosts hair growth in women with hair loss and may help fight microbes and prevent respiratory issues in COVID-19.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

DNA methylation changes are linked to hair growth cycles in goats.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.