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Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Mutations in certain receptors can cause diseases and offer new treatment options.

Finasteride may improve prostate cancer treatment outcomes.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

We need better ways to test and understand SARMs to make safer and more effective treatments.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

The Hairless gene is crucial for healthy skin and hair growth.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

CDP is crucial for lung and hair follicle cell development.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.