research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
Search
for
Sort by
Research
30-60 / 1000+ results 
research DrugNet: Network-Based Drug–Disease Prioritization by Integrating Heterogeneous Data
DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.
research Evaluating the Disease-Related Experiences of TikTok Users With Lupus Erythematosus: Qualitative and Content Analysis
TikTok videos show that people with Lupus often discuss symptoms and their significant impact on mental health, face diagnostic delays, have mixed views on treatments, and feel isolated despite support.
research Evaluating the Disease-Related Experiences of TikTok Users With Lupus Erythematosus: Qualitative and Content Analysis
Lupus patients on TikTok feel isolated, face medical gaslighting, and prefer non-drug treatments.
research Identification of an Osteopontin-Derived Peptide That Binds Neuropilin-1 and Activates Vascular Cells
FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.
research Bayesian Hidden Markov Modeling of Blood Type Distribution for COVID-19 Cases Using Poisson Distribution
Blood type affects COVID-19 infection rates differently in Europe and Africa.
research Advances and Challenges in the Treatment of Skin Diseases with the Transdermal Drug Delivery System
New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.
research An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review
Better hair loss models needed for research.
research Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease
Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
research Real-Life Experience with Belimumab in Systemic Lupus Erythematosus: Control of Disease Activity and Flares in a Multicenter Cohort
Belimumab effectively controls SLE disease activity and reduces steroid use.
research Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease Are Characterised by Interferon-γ-Expressing Th1 Cells and IL-17A/IL-22-Expressing Th17 Cells and Respond to Anti-IL-12/IL-23 Antibody Treatment
Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
research Alopecia Areata Is Associated With Increased Expression of Heart Disease Biomarker Cardiac Troponin I
People with alopecia areata have higher levels of a heart disease marker than those without hair loss.
research Psychodermatology in the UK: Psychological Impact of Skin Diseases and Importance of Services
Mindfulness reduces anxiety and depression in skin disease patients; dermatologists and psychiatrists often lack confidence in treating psychodermatological conditions.
research The Rotterdam Study: 2014 Objectives and Design Update
The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research Chaos and Antichaos in Pathology
Understanding chaos and control mechanisms in disease can improve diagnosis and prediction in medicine.
research Assessing a Measure for Quality of Life in Patients with Severe Alopecia Areata: A Multicentric Italian Study
Alopecia Areata severely impacts mental health, causing anxiety and depression, affecting quality of life.
research Mechanical Anisotropy of Hair Affected by Genetic Diseases Highlights Structural Information Related to Differential Crosslinking in Keratins
research The Protective Effect of the Crosstalk Between Zinc Hair Concentration and Lymphocyte Count: Preliminary Report
Zinc levels and lymphocyte counts might be important in heart disease development.
research Cardiovascular Profile of Pharmacological Agents Used for the Management of Polycystic Ovary Syndrome
Medications for PCOS don't seem to raise heart disease risk.
research Dynamic Evaluation of Pathological Changes in a Mouse Acne Model by Optical Imaging Technology
New imaging techniques can assess and track changes in mouse acne without harm, aiding treatment choices.
research Trichoscopy Features of Indonesian Males with Androgenetic Alopecia in Association with Disease Severity
The research found no clear link between the severity of male baldness and the scalp examination findings in Indonesian men.
research The Use of Mesenchymal Stromal Cells in the Treatment of Coronavirus Disease 2019
Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
research Glucocorticoid-Induced Side Effects Cause Oral Lesions in Systemic Lupus Erythematosus: A Case Report
Glucocorticoid treatment in lupus can cause oral lesions, which need early diagnosis and comprehensive care.
research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Androgens Protect Against Apolipoprotein E4-Induced Cognitive Deficits
Androgens can help prevent memory problems caused by apoE4.
research Treatment of Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective, Real-Life Analysis in a Tertiary Center in Germany
Systemic treatments like hydroxychloroquine and cyclosporine A help with Lichen Planopilaris and Frontal Fibrosing Alopecia, but ongoing treatment is needed.
research Trilostane Treatment of 78 Dogs With Pituitary-Dependent Hyperadrenocorticism
Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.